Until recently, estimates suggested that 2 billion people were latently infected with Mycobacterium tuberculosis. This put about a quarter of the world’s population at risk of “reactivating” their latent infection to develop TB at any time, even decades after their initial infection.
But Professor Lalita Ramakrishnan, a researcher at the University of Cambridge who studies the pathogenesis of TB, along with Professors Marcel Behr from McGill University and Paul Edelstein from the University of Pennsylvania, analyzed five decades worth of published epidemiology research studies and concluded that the number of latently infected individuals is much smaller than previously thought.
In an interview, Prof. Ramakrishnan talked about these findings and the implications for future vaccine research.
Access the full interview here.
For more TB news, check out the latest edition of the TB Online Weekly Newsletter (#6, 20 February 2024) with the latest TB advocacy and research updates.
Source : IAVI
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