Gene editing with CRISPR/Cas9 can lead to unwanted ‘cuts’ and changes in the gene sequences nearby the anchored HIV genome, Dutch researchers report in the Journal of Virology. This might activate genes that could contribute to cancer development, raising concerns about this potential HIV cure strategy.
Gene editing technologies are expected to revolutionise modern medicine and treatment approaches for many diseases. There are currently several strategies for a potential HIV cure, including gene editing – as it is thought to have the potential to permanently remove the virus from most or all bodily cells. Another possibility would be introducing new or modified genes in our cells that make them resistant to the virus. However, there are risks associated with any intervention dealing with our genes.
Read the full story at Aidsmap.
Source : Aidsmap
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