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Acquired rifampicin resistance more likely in HIV-coinfected patients

Patients with HIV and tuberculosis were more likely to develop acquired rifampicin resistance when treated with a thrice-weekly tuberculosis treatment compared with patients not coinfected with HIV, according to researchers from the National Institute for Research in Tuberculosis in India. “[Antiretroviral therapy] reduces but does not eliminate the risk of [acquired...


Source Source: Healio

Arab region has world’s fastest growing HIV epidemic

BEIRUT, Sep 1 2014 (IPS) - At a time when HIV rates have stabilised or declined elsewhere, the epidemic is still advancing in the Arab world, exacerbated by factors such as political unrest, conflict, poverty and lack of awareness due to social taboos. According to UNAIDS (the Joint United Nations Programme on HIV/AIDS), an estimated 270,000 people were living with human...


Source Source: IPS

New tuberculosis blood test in children is reliable and highly specific

A new blood test provides a fast and accurate tool to diagnose tuberculosis in children, a new proof-of-concept study shows. The newly developed test (TAM-TB assay) is the first reliable immunodiagnostic assay to detect active tuberculosis in children. The test features excellent specificity, a similar sensitivity as culture tests in combination with speed of a blood test. The...


Kidney signal trouble worsens over 5 years in Japanese on TDF

Estimated glomerular filtration rate (eGFR), a signal of kidney function, declined steadily over 5 years in HIV-positive Japanese taking tenofovir (TDF) compared with those taking abacavir. The TDF group did worse than the abacavir group by three eGFR measures. The risk TDF poses to kidney function is well appreciated. But the long-term renal impact of TDF in people who continue...


Global research reaches for consensus on HIV treatment response

THE body’s natural reaction to infection is responsible for potentially fatal side-effects of antiretroviral therapy in patients with HIV, according to research. Studies conducted over 10 years ago by Perth immunologist Professor Martyn French and his team are now being backed up by large American studies. The studies are centered on tuberculosis-associated immune...