FDA: Victrelis label updated
Victrelis (boceprevir) label updated for drug-drug interactions.
On July 31, 2012, FDA updated the Victrelis (boceprevir) label to include drug-drug interactions between Victrelis and cyclosporine, tacrolimus, escitalopram, atorvastatin and pravastatin. The main changes to the label are highlighted below.
Changes were also made to the Medication Guide to reflect the new interaction data.
Section 7: Drug Interactions was updated to include information regarding the following drug-drug interactions:
Section 12: Clinical Pharmacology was updated to include the magnitude of interaction between boceprevir and these medications.
Victrelis is a protease inhibitor for the treatment of HCV infection and manufactured by Merck Sharp & Dohme Corp, a subsidiary of Merck & Co.
The complete, revised label and Medication Guide can be viewed at Drugs@FDA.