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Scientific research

HIV-1 genetic diversity is higher in vaginal tract than in blood during early infection

A first-of-its-kind study has found that the genetic diversity of human immunodeficiency virus type 1 (HIV-1) is higher in the vaginal tract than in the blood stream during early infection.…

Antibodies show effectiveness for HIV prevention and promise for treatment and cure

The ability of HIV to mutate has been a major challenge to vaccine development. As the body produces antibodies to target the outer HIV envelope protein, this protein changes, thwarting…

Gene therapy using CAR T-cells could provide long-term protection against HIV

FINDINGS Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected…

New long-acting, less-toxic HIV drug suppresses virus in humanized mice

A team of Yale researchers tested a new chemical compound that suppresses HIV, protects immune cells, and remains effective for weeks with a single dose. In animal experiments, the compound…

Give another push for EMIS and ECHOES!

Both European surveys: EMIS2017 (for MSM) and ECHOES (for community health workers working with MSM) are still open. Both surveys are available in several different European languages. ECHOES: We invite Community…

Why finding new HIV targets takes so long: Some basics about basic research

Although great strides have been made at combating human immunodeficiency virus, leading to better quality of life and a longer life expectancy for those living with the virus, significant problems…

Selective suppression of inflammation could deplete HIV and control HIV activation

A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research. When culturing cells…

Anti-virus protein in humans may resist transmission of HIV-1 precursor from chimps

Cross-transmission of HIV-1 precursor may have started in people with unstable forms of the protein In humans, an anti-virus protein known as APOBEC3H may defend against cross-species transmission from chimpanzees…

Using viruses to fight viruses: new approach eliminates ‘dormant’ HIV-infected cells

While Ottawa researchers are known for their work on cancer-fighting viruses, one team is applying these viruses to a new target: HIV. Researchers at The Ottawa Hospital and the University…

EFGCP Conference Coming Up in February

The upcoming conference of the European Forum for Good Clinical Practice holds its next conference in Brussels in February 2018. The conference will pay special attention to the consequences of…

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