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Scientific research

Chemically modified drug shows promise for HIV treatment, elimination

In a significant breakthrough that could hasten an eventual HIV cure, a research team at UNMC has changed the chemical structure of an existing antiviral drug to facilitate it in…

Big data methods learn the fitness landscape of the HIV Envelope protein

Despite significant advances in medicine, an effective vaccine for the human immunodeficiency virus (HIV) is still not available, although recent hope has emerged through the discovery of antibodies capable of…

Scientists report big improvements in HIV vaccine production

Technical advances in vaccine production should shorten the time to clinical trials, breaking the logjam of promising new candidate vaccines waiting to be tested Research on HIV over the past…

How viruses disarm the immune system

Discovery of molecular mechanism could point toward new targets for treating patients How do viruses that cause chronic infections, such as HIV or hepatitis C virus, manage to outsmart their…

Recruiting natural killer cells to target HIV persistence

An important goal in HIV cure research is the identification of immune responses that might be induced or enhanced to promote clearance of virus-infected cells. The main focus of this…

Progress toward an HIV cure highlighted in annual special issue of AIDS Research and Human Retroviruses

New Rochelle, NY, January 25, 2018—Researchers have shown that despite effective combined antiretroviral therapy (cART), HIV can hide in the spleen of patients with no detectable HIV in their blood.…

American Gene Technologies announces progress toward Phase I clinical trial of AGT103-T for HIV functional cure

Completes process development for the AGT103-T automated cell manufacturing protocol ROCKVILLE, Md., Jan. 25, 2018 -- American Gene Technologies International Inc. (AGT), a leading gene and cell therapy company, today…

Study links gut-homing protein levels with HIV infection risk, disease progression

NIH clinical trial is testing antibody against the protein in people with HIV. For the first time, scientists have shown a relationship between the proportion of key immune cells that…

January 2018 issue of Journal of Virus Eradication now online

The January issue of the Journal includes reports from the First EPIICAL General Assembly meeting (Rome, Italy), the HTLV-1 symposium at the 2017 Australasian HIV and AIDS Conference (Canberra, Australia),…

Researchers find latent HIV reservoirs inherently resistant to elimination by CD8+ T-cells

The study performed at the George Washington University presents a possible obstacle in finding a cure for HIV WASHINGTON (Jan. 22, 2018) -- The latest "kick-and-kill" research to eliminate the…