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Scientific research

Scientists develop tool to measure success of HIV cure strategies

Scientists funded by the National Institutes of Health have developed a new assay to accurately and easily count the cells that comprise the HIV reservoir, the stubborn obstacle to an…

Scientists reveal how a “closed” protein structure helps HIV dodge antibodies

HIV is a master of sneaking past our natural defenses. Typically, when the body encounters a harmful virus, immune cells recognize viral proteins and stimulate the production of protective proteins…

Scientists examine how an immune system protein helps suppress HIV

Much of the research on HIV has focused on preventing infection but little is understood about how the body keeps the virus in check post-infection. A new study by Yale…

Larger HIV reservoirs found in those with clade B subtype

A study team led by investigators from Simon Fraser University in Canada have made a key discovery on how viral factors, such as HIV subtypes, impact the size of the…

HIV protein function that slows migration of T cells also improves viral survival

"Patch" of Nef protein amino acids appears to help virus evade the immune response in animal model A study from a Massachusetts General Hospital (MGH) research team has identified the…

Cell size and cell-cycle states play key decision-making roles in HIV

Thanks to the development of antiretroviral drugs, human immunodeficiency virus (HIV) is considered a manageable chronic disease today. However, if left undiagnosed or untreated, HIV can develop into AIDS (acquired…

AIDS – an approach for targeting HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified…

Uncovering a key mechanism in assembly of Avian Sarcoma Virus, a relative of HIV-1

This 100-year-old oncogenic virus often used to study HIV-1, and understanding the molecular basis of binding informs ways to prevent retroviral replication, including the HIV retrovirus. BIRMINGHAM, Ala. - A…

Hepatitis: Liver failure attributable to compromised blood supply

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich (TUM) has now discovered how this occurs: by immune cells…

HIV vaccine protects non-human primates from infection

LA JOLLA, CA, December 14, 2018 – For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research,…