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Scientific research

Early antiretroviral treatment may preserve key immune responses to HIV

Ragon Institute study findings could pave the way to vaccine development Instituting combination antiretroviral (ART) treatment at the earliest stages of HIV infection may allow the generation of functional CD8…

TB Alliance and partners form multidisciplinary center for translational TB drug research

New collaboration, supported by U.S. National Institutes of Health, to produce two new clinical stage TB drug candidates NEW YORK, NY (May 9, 2019)—The National Institute of Allergy and Infectious…

New HIV vaccine strategy “pumps” the immune system

LJI scientists find that slowly releasing an HIV vaccine could prompt the body to make more powerful antibodies against the virus LA JOLLA, CA – A new HIV vaccine delivery…

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of…

NIH awards will advance development of vaccines for sexually transmitted infections

NIAID announces four new cooperative research centers. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced awards to establish four Cooperative…

Study presents drug candidate for reversing mucosal barrier damage by HIV

A vaginal microbicide that could prevent sexual transmission of HIV-1 in women has tremendous potential for saving lives and helping staunch an epidemic. But the delicate milieu of microbes that…

TAGline May 2019: Nothing about us without us

This TAGline is all about the importance of community engagement in research to end the epidemics of HIV, HCV, and TB. As this edition’s cover shows, protestors at the “Storm…

Ragon Institute study identifies viral peptides critical to natural HIV control

T-cell targeting of essential amino acids may underlie spontaneous HIV suppression, define path to a vaccine Investigators at the Ragon Institute of MGH, MIT and Harvard have used a novel approach…

Tulane University awarded $6.1 million for postnatal HIV, TB study

Tuberculosis, the world’s leading infectious disease killer, is also the leading cause of death in infants with HIV. Researchers at Tulane National Primate Research Center will use a new $6.1…

Designer drugs to inhibit hepatitis A virus

Structure-based drug design revealed that a compound previously investigated for the treatment of head-and-neck cancer could function as a lead compound for the development of drugs to treat hepatitis A…