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Scientific research

Last unknown structure of HIV-1 solved, another step in efforts to disarm the AIDS virus

A University of Alabama at Birmingham team led by Jamil Saad, Ph.D., has solved the last unknown protein structure of HIV-1, the retrovirus that can cause AIDS. Knowledge of this…

New research opens the door to ‘functional cure’ for HIV

JUPITER, FL – October 17, 2017 – In findings that open the door to a completely different approach to curing HIV infections, scientists from the Florida campus of The Scripps…

Reservoir explorers find extra HIV/SIV pond

Scientists at Yerkes National Primate Research Center, Emory University have identified an additional part of the HIV reservoir, immune cells that survive and harbor the virus despite long-term treatment with…

One if by editing, two if by roadblock: Human protein fights HIV as both monomer and dimer

Fifteen years ago, a class of proteins was discovered, which give humans innate immunity to HIV-1. Unfortunately, HIV-1 is a smart virus and has evolved to battle these proteins. Northeastern…

Reengineered immune system cells show early promise against HIV

Improving on a previous attempt, scientists have developed a new strategy that could potentially be used to reengineer a patient's own immune system cells to fight HIV. The approach, described…

Revamped CAR-T could curb HIV levels without antiretroviral drugs

While antiretroviral drugs effectively keep HIV at very low levels, they do not eliminate the virus. If a patient is taken off treatment, or doesn’t stick to his or her…

October 2017 issue of Journal of Virus Eradication now online

Researchers create molecule that could ‘kick and kill’ HIV

In lab animals, a particle developed by UCLA, Stanford, NIH scientists awakens dormant virus cells and then knocks them out Current anti-AIDS drugs are highly effective at making HIV undetectable…

Scientists bring new insights into the heritability of HIV infection severity

HIV's pernicious persistence in human populations -- despite more than 25 years of heroic HIV research efforts --owes in part to its particular abilities to exploit its human hosts, constantly…

When HIV drugs don’t cooperate

The term “synergy” has gained a reputation as an overused buzzword, but it has a quantifiable definition in pharmacology. Two drugs are considered synergistic when their effectiveness when used together…