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Scientific research

Using crystals to unpick how viruses work

Researchers at Cardiff University have used x-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection. The new insight could help in…

Using anti-cancer immunotherapy to fight HIV

CRCHUM researchers are exploring a potential therapeutic approach Researchers at the University of Montreal Hospital Research Centre (CRCHUM) have shown that immunotherapy treatments against cancer could reduce the amount of…

Engineered immune cells produce antibodies to fight HIV

Cells removed from patients’ bloodstreams and genetically altered may allow more effective vaccines for HIV, influenza, hepatitis LA JOLLA, CA, February 12, 2019 — Scripps Research scientists have successfully re-engineered human B…

First evidence of HIV reservoirs in macrophages

Basic scientists in France have recently discovered that macrophages located in urethral tissue can contribute to cellular HIV reservoirs, and that the quantity of these specific immune cells is surprisingly…

New discovery could lead to ways to protect HIV patients from deadly TB

Director of the Southwest National Primate Research Center Professor Deepak Kaushal, Ph.D. says research he collaborated on is pinpointing a possible new avenue of protection for HIV/AIDS patients. The study, published this month in…

HIV drug could treat Alzheimer’s, age-associated disorders

Research led by Brown found that blocking retrotransposon activity with a generic HIV/AIDS medication significantly reduces age-related inflammation in old mice and senescent human cells, providing hope for treating age-associated…

Diversity in the CD4 receptor protects chimpanzees from infection by AIDS-like viruses

Penn study of the chimpanzee precursor of HIV-1 could lead to a better AIDS vaccine PHILADELPHIA - Beatrice H. Hahn, MD, a professor of Medicine and Microbiology in the Perelman…

HIV-1 protein suppresses immune response more broadly than thought

Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought. Their findings could help inform more…

Cutting-edge approach maps HIV’s escape routes

Atlas of immune-evading HIV mutations could inform design of new treatments, vaccines Using a cutting-edge approach, scientists at Fred Hutchinson Cancer Research Center constructed an atlas of mutations HIV uses…

Researchers link T cell recognition diversity to HIV control

The immune system is the body’s best defense in fighting diseases like HIV and cancer.  Now, an international team of researchers is harnessing the immune system to provide new clues…