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Scientific research

GSK partners with CRISPR pioneer Doudna to search for new drugs

SAN FRANCISCO — The drug maker GlaxoSmithKline announced Thursday that it would team up with some of the nation’s most prominent CRISPR researchers to use the gene-editing technology in a…

In wake of Trump’s fetal tissue clampdown, scientists strain to adjust

Megan Sykes, an immunologist at Columbia University, has spent years using human fetal tissue to develop a mouse with a humanlike immune system, which mimics how type 1 diabetes develops…

Is it safe to alter the CCR5 receptor? And how will this influence HIV cure studies?

The HIV cure effort suffered a potential setback this week, as researchers reported an association between having two copies of the CCR5-∆32 mutation and shorter survival. Read the full blog post…

NIH HIV experts prioritize research to achieve sustained ART-free HIV remission

Achieving sustained remission of HIV without life-long antiretroviral therapy (ART) is a top HIV research priority, according to a new commentary in JAMA by experts at the National Institute of…

Trump administration restricts federal research involving fetal tissue

Ends University of California, San Francisco project using tissue to test HIV treatments Associated Press: Trump halts fetal tissue research by government scientists “The Trump administration said Wednesday that it is ending…

Immune cells play unexpected role in early TB infection

Discovery may provide a new target for TB drugs, vaccines, NIH-supported research suggests A class of immune cells called innate lymphoid cells (ILCs) mediates the body’s initial defense against tuberculosis…

CRISPR baby mutation significantly increases mortality

Two copies of mutated CCR5 gene associated with lower survivability A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them…

Half of HIV patients are women. Most research subjects are men.

Trials of vaccines and treatments have not included enough female participants. Now that scientists are exploring possible cures, the need to enroll women is greater than ever. Inspired by reports of…

Could gold be the key to making gene therapy for HIV, blood disorders more accessible?

Gold nanoparticles loaded with CRISPR and other gene-editing tools safely and effectively edited blood stem cells Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy…

Monkey-infecting virus may provide part of future HIV vaccine

Simian immunodeficiency virus envelope protein elicits desired anti-HIV antibody response in mice LA JOLLA, CA – A protein from Simian Immunodeficiency Virus (SIV), which can infect monkeys and apes, has…