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Scientific research

Engineered immune cells produce antibodies to fight HIV

Cells removed from patients’ bloodstreams and genetically altered may allow more effective vaccines for HIV, influenza, hepatitis LA JOLLA, CA, February 12, 2019 — Scripps Research scientists have successfully re-engineered human B…

First evidence of HIV reservoirs in macrophages

Basic scientists in France have recently discovered that macrophages located in urethral tissue can contribute to cellular HIV reservoirs, and that the quantity of these specific immune cells is surprisingly…

New discovery could lead to ways to protect HIV patients from deadly TB

Director of the Southwest National Primate Research Center Professor Deepak Kaushal, Ph.D. says research he collaborated on is pinpointing a possible new avenue of protection for HIV/AIDS patients. The study, published this month in…

HIV drug could treat Alzheimer’s, age-associated disorders

Research led by Brown found that blocking retrotransposon activity with a generic HIV/AIDS medication significantly reduces age-related inflammation in old mice and senescent human cells, providing hope for treating age-associated…

Diversity in the CD4 receptor protects chimpanzees from infection by AIDS-like viruses

Penn study of the chimpanzee precursor of HIV-1 could lead to a better AIDS vaccine PHILADELPHIA - Beatrice H. Hahn, MD, a professor of Medicine and Microbiology in the Perelman…

HIV-1 protein suppresses immune response more broadly than thought

Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought. Their findings could help inform more…

Cutting-edge approach maps HIV’s escape routes

Atlas of immune-evading HIV mutations could inform design of new treatments, vaccines Using a cutting-edge approach, scientists at Fred Hutchinson Cancer Research Center constructed an atlas of mutations HIV uses…

Researchers link T cell recognition diversity to HIV control

The immune system is the body’s best defense in fighting diseases like HIV and cancer.  Now, an international team of researchers is harnessing the immune system to provide new clues…

Scientists develop tool to measure success of HIV cure strategies

Scientists funded by the National Institutes of Health have developed a new assay to accurately and easily count the cells that comprise the HIV reservoir, the stubborn obstacle to an…

Scientists reveal how a “closed” protein structure helps HIV dodge antibodies

HIV is a master of sneaking past our natural defenses. Typically, when the body encounters a harmful virus, immune cells recognize viral proteins and stimulate the production of protective proteins…

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