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Scientific research

Larger HIV reservoirs found in those with clade B subtype

A study team led by investigators from Simon Fraser University in Canada have made a key discovery on how viral factors, such as HIV subtypes, impact the size of the…

HIV protein function that slows migration of T cells also improves viral survival

"Patch" of Nef protein amino acids appears to help virus evade the immune response in animal model A study from a Massachusetts General Hospital (MGH) research team has identified the…

Cell size and cell-cycle states play key decision-making roles in HIV

Thanks to the development of antiretroviral drugs, human immunodeficiency virus (HIV) is considered a manageable chronic disease today. However, if left undiagnosed or untreated, HIV can develop into AIDS (acquired…

AIDS – an approach for targeting HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified…

Uncovering a key mechanism in assembly of Avian Sarcoma Virus, a relative of HIV-1

This 100-year-old oncogenic virus often used to study HIV-1, and understanding the molecular basis of binding informs ways to prevent retroviral replication, including the HIV retrovirus. BIRMINGHAM, Ala. - A…

Hepatitis: Liver failure attributable to compromised blood supply

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich (TUM) has now discovered how this occurs: by immune cells…

HIV vaccine protects non-human primates from infection

LA JOLLA, CA, December 14, 2018 – For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research,…

Trump quietly shuts down HIV cure research to appease the religious right

Scientists are speaking out against a directive by the Trump administration that has shut down research into a cure for HIV. A scientist who was supposed to supply mice that…

Roadmap reveals shortcut to recreate key HIV antibody for vaccines

With new insights about the antibody's pathway, researchers can bypass a previous hurdle DURHAM, N.C. -- HIV evades the body's immune defenses through a multitude of mutations, and antibodies produced…

CRISPR-Cas9: a world first?

On Nov 26, when the world heard the claims that the first genetically edited children had been born, the reaction was one of deep and profound shock. He Jiankui announced…

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