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Pediatrics

Breaking the cycle: Paediatric DR-TB detection, care and treatment in Tajikistan

The Tajik Ministry of Health and Médecins Sans Frontières (MSF) began a comprehensive paediatric tuberculosis (TB) care programme in 2011. The paediatric TB project in Dushanbe aims to decrease the…

Could an infant’s blood sample help model a better HIV vaccine?

Tracing the evolution of a baby’s special HIV-blocking protein Forward progress sometimes requires a backward glance. A twenty-five-year-old blood sample from an infant infected with HIV could hold clues to…

Point-of-care technology for early infant HIV diagnosis speeds up return of HIV test results

Point-of-care testing for early infant HIV diagnosis is highly effective in reducing turnaround time for HIV test results, enabling earlier antiretroviral treatment initiation in infants, in sub-Saharan Africa. An observational…

Needleless vaccine will protect children from dangerous viruses

Orally administered vaccine can protect millions from hepatitis B. Oral vaccines are both safer and less expensive than injections; researchers are continuously pursuing ways to produce an oral vaccine that…

Why has the uptake of lopinavir/ritonavir oral pellets for children been slow?

Lopinavir/ritonavir (LPV/r) oral pellets and oral granules for infants and young children living with HIV have proven advantages in terms of efficacy and tolerability over other formulations of LPV/r, but…

International $6 million grant to study HIV/TB coinfection in kids

PITTSBURGH, 1/5/2019 – About a third of us are walking around with the bacteria that causes tuberculosis (TB) in our bodies, but most don’t actually end up with TB. For…

FDA approves first treatment for all genotypes of hepatitis C in pediatric patients

The U.S. Food and Drug Administration today (April 30) approved Mavyret (glecaprevir and pibrentasvir) tablets to treat all six genotypes of hepatitis C virus (HCV) in children ages 12 to…

Infants exposed to HIV have greater risk of RSV-related hospitalizations

HIV exposure significantly increased the risk of hospitalization for respiratory syncytial virus (RSV) infections among infants younger than 5 months, according to a recent study in South Africa. RSV causes…

Benefit of early ART initiation in HIV-infected children and adolescents

Early initiation of antiretroviral therapy (ART) and improved nutrition in children with HIV were positively associated with lung function and represent important modifiable factors, according to study results published in PLoS…

US revises pediatric HIV treatment guidelines

Changes include new information about risks associated with Tivicay during pregnancy and a removal of older drugs owing to toxicities. The Department of Health and Human Services has revised its…

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