EATG » Immune response

Immune response

Inflammation triggers unsustainable immune response to chronic viral infection

Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development.…

Clinicians urged to manage HIV-infected elders differently from younger people

Differences in immune response to antiretroviral therapy, multimorbidity and antiretroviral toxicities are among the factors that differentiate older adults with HIV from their younger counterparts, and should influence care plans,…

Understanding sequential immunization strategies

How are researchers using a step-wise approach to try to train the immune system to fend off HIV? Antibodies are one of the main ways the body fights off infection.…

Crohn’s disease drug produces long-lasting viral undetectability and T-cell restoration off treatment in monkeys

Novel immune signature seen: resembles response to first partially effective HIV vaccine In a promising experiment in rhesus macaque monkeys, scientists from Emory University in Atlanta have used a monkey-adapted…

Imperfect adherence to HIV meds may spur harmful inflammation

This may occur even when people living with the virus have an undetectable viral load Less-than-perfect adherence to an HIV treatment regimen may not send viral loads into detectable territory…

Cells infected by HIV defend themselves, research shows

T cells, important in the immune system, defend themselves when infected by HIV (human immunodeficiency virus). Until now, it was considered that these cells were not aware of their infection…

People 60 or older gain fewer CD4s on ART through 48 months

People starting antiretroviral therapy (ART) at age 60 or older gained substantially fewer CD4 cells through 48 months than 20-to-29-year-olds, according to analysis of almost 160,000 people in Africa .…

Broadly neutralizing HIV antibodies pave the way for vaccine

A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types…

Study explores potency of antibodies to combat HIV infection

Rutgers' New Jersey Medical School is selected as test site for novel study Rutgers' New Jersey Medical School's Clinical Research Center (NJMS-CRC) is participating as a clinical trial site in…

Scientists discover antibodies that target holes in HIV’s defenses

New findings could lead to new AIDS vaccine candidates LA JOLLA, CA – September 12, 2016 – A new study from scientists at The Scripps Research Institute (TSRI) shows that…