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Immune response

CROI 2018: NATAP reports

Conference on Retroviruses and Opportunistic Infections (CROI), 4-7 March 2018, Boston, Massachusetts, USA Multiple low doses of nucleoside MK-8591 strong in healthy volunteers Integrase inhibitor penetration generally worse in lymphoid…

Issue brief: Suboptimal immune recovery on antiretroviral therapy

Treatment Action Group released an issue brief: Suboptimal immune recovery on antiretroviral therapy. It can be accessed here.

CROI 2018: PCSK9 levels raised in asymptomatic HIV patients

Levels of proprotein convertase sutilisin/kexin 9 (PCSK9), the enzyme encoded on chromosome 1, are elevated in asymptomatic patients with HIV — possibly giving researchers another resource by which to diagnose…

Tweak to broadly neutralizing HIV antibody makes it last longer

Researchers are trying to harness the power of certain antibodies as long-acting injectable forms of HIV treatment or PrEP. Researchers have found that a slight modification to the broadly neutralizing…

Cannabis associated with immune cell frequency reduction in ART-treated HIV patients

A recent study found that cannabis use is associated with a potentially beneficial reduction in systemic inflammation and immune activation in the context of antiretroviral therapy (ART)-treated HIV-infected individuals. Findings…

Infection site affects how a virus spreads through the body

Different routes of sexual transmission affect the immune system’s response to a virus, shows new study San Francisco, CA—A person is more likely to get infected by HIV through anal…

Argos announces issuance of patent covering the foundation for manufacturing its HIV immunotherapy

Patent related to strain-independent amplification of HIV nucleic acid sequences DURHAM, N.C., Feb. 15, 2018 -- Argos Therapeutics Inc. (NASDAQ:ARGS), an immuno-oncology company focused on the development and commercialization of…

Promising drug target could restore immune system’s ability to fight HIV

Scientists in NCI’s Center for Cancer Research have identified a new target for drugs that could help people who are HIV-positive eliminate recalcitrant pools of the virus. The research findings…

How viruses disarm the immune system

Discovery of molecular mechanism could point toward new targets for treating patients How do viruses that cause chronic infections, such as HIV or hepatitis C virus, manage to outsmart their…

Recruiting natural killer cells to target HIV persistence

An important goal in HIV cure research is the identification of immune responses that might be induced or enhanced to promote clearance of virus-infected cells. The main focus of this…