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Immune response

Different diseases elicit distinct sets of exhausted T cells

Epigenomics survey of human immune cells has implications for fighting chronic infections, autoimmunity, and cancer The battle between the human immune system and long-term, persisting infections and other chronic diseases…

Universal antibody drug for HIV-1 prevention and immunotherapy

A research team led by scientists at AIDS Institute and Department of Microbiology, Li Ka Shing Faculty of Medicine of The University of Hong Kong (HKU) invents a universal antibody…

Researcher finds link between crystal methamphetamine and immune changes in HIV

A researcher at the University of Miami Miller School of Medicine has found that the use of stimulants such as methamphetamine can negatively affect the health of HIV-positive people even…

HIV cell dysfunction discovery sheds light on how virus works

A new study has revealed that certain immune cells behave differently in HIV-infected patients than they do in healthy individuals. A team of chemical and biomedical engineers from the Cockrell…

CATIE: March/April 2018 issue of TreatmentUpdate now online

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 226: Inflammation, March/April 2018 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-226/inflammation

Integral Molecular’s protein engineering technology facilitates HIV vaccine development

PHILADELPHIA, March 13, 2018 - Integral Molecular, the industry leader in engineering membrane proteins, has extended its protein engineering capabilities to stabilize viral proteins and produce more effective candidate vaccines…

CATIE: February 2018 issue of TreatmentUpdate now online

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 225: Inflammation, HIV and marijuana, February 2018 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-225/inflammation-hiv-and-marijuana

CROI 2018: NATAP reports

Conference on Retroviruses and Opportunistic Infections (CROI), 4-7 March 2018, Boston, Massachusetts, USA Multiple low doses of nucleoside MK-8591 strong in healthy volunteers Integrase inhibitor penetration generally worse in lymphoid…

Issue brief: Suboptimal immune recovery on antiretroviral therapy

Treatment Action Group released an issue brief: Suboptimal immune recovery on antiretroviral therapy. It can be accessed here.

CROI 2018: PCSK9 levels raised in asymptomatic HIV patients

Levels of proprotein convertase sutilisin/kexin 9 (PCSK9), the enzyme encoded on chromosome 1, are elevated in asymptomatic patients with HIV — possibly giving researchers another resource by which to diagnose…