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Immune response

New research shows abnormal immune activation even in very early HIV infection

Even in very early (acute) HIV infection—before fourth generation HIV test assays are able to detect an HIV infection—immune activation and inflammatory processes may already be occurring, new research shows.…

Researchers find new therapeutic target against chronic viral infections

There are a number of things that can impact our immune system’s ability to eliminate a virus; the expression levels of particular proteins—specifically interferon proteins—is one of them. In the…

Protein that activates immune response harms body’s ability to fight HIV

UCLA-led researchers suggest that blocking type I interferon may help combat the virus that causes AIDS In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a…

Does vitamin D boost vaccine immune response in HIV-infected patients?

In an article published in PLOS ONE, Professor Jean-Paul Viard, MD, from the Assistance Publique–Hôpitaux de Paris, and colleagues, explore a potential link between higher basal vitamin D levels in…

Advocates call for more research on immune-enhancing therapies for people with HIV

HIV/AIDS activists recently issued a call for expanded research to accelerate the development of immune-enhancing therapies for HIV-positive immunological non-responders -- people who achieve viral suppression on antiretroviral therapy but…

NIH scientists identify potent antibody that neutralizes nearly all HIV strains

Scientists from the National Institutes of Health have identified an antibody from an HIV-infected person that potently neutralized 98 percent of HIV isolates tested, including 16 of 20 strains resistant…

New research shows promise for immunotherapy as HIV treatment

Study demonstrated modest control of HIV and identified pre-existing drug resistance as an important barrier to antibody-based immunotherapy PHILADELPHIA, November 9 — Immunotherapy has revolutionized treatment options in oncology, neurology,…

Two genes linked to postpartum immunity revival in women with persistent hepatitis C

Research may provide a model for identifying immune factors needed to control chronic infections Alternative forms of two genes are associated with a boost in immunity to hepatitis C after…

Inflammation triggers unsustainable immune response to chronic viral infection

Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development.…

Clinicians urged to manage HIV-infected elders differently from younger people

Differences in immune response to antiretroviral therapy, multimorbidity and antiretroviral toxicities are among the factors that differentiate older adults with HIV from their younger counterparts, and should influence care plans,…