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Immune response

CD4 count recovery: French study reaffirms why it is important to test and treat HIV early

Seven-in-ten people with HIV taking combined antiretroviral therapy for the first time recover their CD4 cell count to above 500 cells/mm3, French researchers report in AIDS. Having a higher CD4…

Novel mechanism of immune activation in HIV-exposed, seronegative people who inject drugs

PHILADELPHIA — (Nov. 13, 2018) — According to new research from The Wistar Institute, the S100A14 protein is expressed at higher levels in people who inject drugs and remain uninfected despite…

Prednisone cuts risk of dangerous immune-system rebound during HIV-TB treatment

Giving low-dose prednisone soon after initiation of HIV therapy to people who are both infected with tuberculosis and have very low CD4 counts can prevent their immune system from dangerously…

Absolute CD4 cell count may predict mortality in HIV/HCV coinfection

Absolute CD4 cell count may predict disease progression and death in individuals coinfected with HIV and hepatitis C virus (HCV), according to a study published in AIDS Research and Human Retroviruses.1…

IAVI and Serum Institute of India to develop and manufacture globally affordable and accessible antibody products for HIV

NEW YORK – October 22, 2018 – The International AIDS Vaccine Initiative (IAVI) and Serum Institute of India, the world’s largest vaccine manufacturer, today announced a strategic partnership to develop and…

Why do some people produce HIV-fighting antibodies? Duke researchers may have an answer

Duke researchers have recently discovered why some people can produce antibodies capable of fighting HIV, and the answer might lie in one special protein. The study focused on better understanding…

Special antibodies could lead to HIV vaccine

Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against…

New antibody analysis accelerates rational vaccine design

Scripps Research study illuminates humoral immune response to experimental vaccines. A team at Scripps Research has come up with a faster way to analyze the outcome of experimental vaccines against…

Swift gene-editing method may revolutionize treatments for cancer and infectious diseases

Scientists report that they have discovered a way to tweak genes in the body’s immune cells by using electrical fields. For the first time, scientists have found a way to…

Imaging technique illuminates immune status of monkeys with HIV-like virus

Approach could improve understanding of immune system recovery in people treated for HIV infection Findings from an animal study suggest that a non-invasive imaging technique could, with further development, become…

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