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Immune response

‘Left behind’: Drug companies and researchers have overlooked patients who don’t respond to HIV meds

To look at Nelson Vergel, you would never guess what he has been through. For 35 years, he has kept up a relentless fight against HIV, but his muscular physique…

Faulty immune receptor could be reason why many face HIV complications

For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues,…

Unique immune cell likely drives chronic inflammation

For the first time, researchers have identified that an immune cell subset called gamma delta T cells that may be causing and/or perpetuating the systemic inflammation found in normal aging…

CD4 count recovery: French study reaffirms why it is important to test and treat HIV early

Seven-in-ten people with HIV taking combined antiretroviral therapy for the first time recover their CD4 cell count to above 500 cells/mm3, French researchers report in AIDS. Having a higher CD4…

Novel mechanism of immune activation in HIV-exposed, seronegative people who inject drugs

PHILADELPHIA — (Nov. 13, 2018) — According to new research from The Wistar Institute, the S100A14 protein is expressed at higher levels in people who inject drugs and remain uninfected despite…

Prednisone cuts risk of dangerous immune-system rebound during HIV-TB treatment

Giving low-dose prednisone soon after initiation of HIV therapy to people who are both infected with tuberculosis and have very low CD4 counts can prevent their immune system from dangerously…

Absolute CD4 cell count may predict mortality in HIV/HCV coinfection

Absolute CD4 cell count may predict disease progression and death in individuals coinfected with HIV and hepatitis C virus (HCV), according to a study published in AIDS Research and Human Retroviruses.1…

IAVI and Serum Institute of India to develop and manufacture globally affordable and accessible antibody products for HIV

NEW YORK – October 22, 2018 – The International AIDS Vaccine Initiative (IAVI) and Serum Institute of India, the world’s largest vaccine manufacturer, today announced a strategic partnership to develop and…

Why do some people produce HIV-fighting antibodies? Duke researchers may have an answer

Duke researchers have recently discovered why some people can produce antibodies capable of fighting HIV, and the answer might lie in one special protein. The study focused on better understanding…

Special antibodies could lead to HIV vaccine

Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against…

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