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Immune response

HIV cell dysfunction discovery sheds light on how virus works

A new study has revealed that certain immune cells behave differently in HIV-infected patients than they do in healthy individuals. A team of chemical and biomedical engineers from the Cockrell…

CATIE: March/April 2018 issue of TreatmentUpdate now online

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 226: Inflammation, March/April 2018 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-226/inflammation

Integral Molecular’s protein engineering technology facilitates HIV vaccine development

PHILADELPHIA, March 13, 2018 - Integral Molecular, the industry leader in engineering membrane proteins, has extended its protein engineering capabilities to stabilize viral proteins and produce more effective candidate vaccines…

CATIE: February 2018 issue of TreatmentUpdate now online

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 225: Inflammation, HIV and marijuana, February 2018 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-225/inflammation-hiv-and-marijuana

CROI 2018: NATAP reports

Conference on Retroviruses and Opportunistic Infections (CROI), 4-7 March 2018, Boston, Massachusetts, USA Multiple low doses of nucleoside MK-8591 strong in healthy volunteers Integrase inhibitor penetration generally worse in lymphoid…

Issue brief: Suboptimal immune recovery on antiretroviral therapy

Treatment Action Group released an issue brief: Suboptimal immune recovery on antiretroviral therapy. It can be accessed here.

CROI 2018: PCSK9 levels raised in asymptomatic HIV patients

Levels of proprotein convertase sutilisin/kexin 9 (PCSK9), the enzyme encoded on chromosome 1, are elevated in asymptomatic patients with HIV — possibly giving researchers another resource by which to diagnose…

Tweak to broadly neutralizing HIV antibody makes it last longer

Researchers are trying to harness the power of certain antibodies as long-acting injectable forms of HIV treatment or PrEP. Researchers have found that a slight modification to the broadly neutralizing…

Cannabis associated with immune cell frequency reduction in ART-treated HIV patients

A recent study found that cannabis use is associated with a potentially beneficial reduction in systemic inflammation and immune activation in the context of antiretroviral therapy (ART)-treated HIV-infected individuals. Findings…

Infection site affects how a virus spreads through the body

Different routes of sexual transmission affect the immune system’s response to a virus, shows new study San Francisco, CA—A person is more likely to get infected by HIV through anal…

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