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HIV treatment

Dolutegravir during pregnancy appears safe

Dolutegravir treatment does not appear to worsen pregnancy or neonatal outcomes, according to a registry study. "While the results are not conclusive because of the small number of pregnancies, neither…

ART interruption with close monitoring, strict restart guidelines safe in HIV cure trials

Analytic treatment interruption, used to determine the efficacy of any therapeutic strategy designed to achieve antiretroviral therapy (ART)-free remission from HIV, caused neither expansion of HIV reservoirs nor immunologic abnormalities…

Benefit of early ART initiation in HIV-infected children and adolescents

Early initiation of antiretroviral therapy (ART) and improved nutrition in children with HIV were positively associated with lung function and represent important modifiable factors, according to study results published in PLoS…

US revises pediatric HIV treatment guidelines

Changes include new information about risks associated with Tivicay during pregnancy and a removal of older drugs owing to toxicities. The Department of Health and Human Services has revised its…

A promising HIV drug poses a dilemma

If you live in a wealthy country, you have choices about your medical care. Let's say you're a young woman who is HIV-positive and find out there's a new treatment…

Novel antibody may suppress HIV for up to four months

NIAID researchers, international collaborators report results of small, open-label study Regular infusions of an antibody that blocks the HIV binding site on human immune cells may have suppressed levels of…

In rare cases, immune system fails despite HIV suppression

NIAID scientists identify paradoxical response to HIV medication in five individuals Antiretroviral therapy (ART) is usually very effective at suppressing HIV in the body, allowing a person’s immune system to…

Weight gain with new antiretrovirals: Its complicated

South Africa’s next big shift in our antiretroviral programme is to replace efavirenz with a newish drug called dolutegravir. The last big change was from stavudine (d4T) to tenofovir, and…

Dual therapy with rilpivirine and boosted darunavir is effective in PLWHIV

Rilpivirine plus boosted-darunavir (RPV + bDRV) dual therapy may be effective and safe in patients with advanced HIV infection and previous virologic failure according to a study recently published in BMC…

Janssen presents new data for SYMTUZA

Janssen presents new data from first Phase 3 trial of a single-tablet regimen in a rapid initiation model of care demonstrating safety and efficacy with SYMTUZA® through 48 weeks --…

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