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Hepatitis

HDV Persists During Liver Regeneration and is Amplified Through Cell Division

Hepatitis delta virus (HDV) persists during liver regeneration by transmitting HDV RNA to dividing cells even in the absence of hepatitis B virus (HBV) coinfection. Therefore the strong persistence capacities of HDV…

Prescribers of opioid substitutes lack funding, facilities and guidelines to treat hepatitis C, global survey reveals

Only thirty percent of physicians who prescribe opioid substitution therapy to people who inject drugs have also prescribed direct-acting antivirals, despite being ideally placed to offer testing and treatment for…

Antiviral therapy may slow renal function decline in hepatitis C

Direct-acting antiviral therapy can slow kidney function decline in patients with hepatitis C (HCV) and chronic kidney disease (CKD), according to new study findings published in Kidney International. Meghan E. Sise,…

Arbutus receives regulatory clearance to initiate Phase 1a/1b clinical trial of AB-729

- AB-729 is a subcutaneously-administered RNAi agent targeting HBV replication and HBsAg antigen production - Supports corporate objective to combine AB-729 with AB-506, Arbutus’ proprietary oral capsid inhibitor WARMINSTER, Pa., June…

Hepatitis B linked to cancers beyond the liver

Study in China sees an association with several cancer types, especially gastrointestinal malignancies. People with chronic hepatitis B virus (HBV) infection may be more likely to develop other malignancies in…

HEV infections among HIV-positive individuals during an outbreak of hepatitis A

Sexual orientation and acquisition of sexually transmitted infections (STIs) are not significantly associated with the occurrence of hepatitis E virus (HEV) infection, according to a study published in Hepatology.1 Both hepatitis A virus…

Universal pregnancy screening for HCV could eliminate transmission in Canada

In a recently published commentary, Chelsea Elwood, MD, from the University of British Columbia, and colleagues advised that Canadian guidelines should recommend universal screening for hepatitis C in pregnant women as they…

Hepatitis C antiviral treatment linked to Parkinson’s

A possible link between hepatitis C infection and Parkinson's disease has been further strengthened by a new study from Taiwan. The study shows that among patients with chronic hepatitis C,…

HCV treatment with Epclusa safe in patients undergoing dialysis for ESRD

Although not currently licensed for patients undergoing dialysis for severe renal impairment, researchers found that treatment with Epclusa for hepatitis C was safe and effective in patients with end-stage renal…

VBI Vaccines announces Phase 3 study results for Sci-B-Vac®

VBI Vaccines announces positive top-line results from PROTECT, a pivotal Phase 3 study of Sci-B-Vac® -- Both co-primary endpoints successfully met – including non-inferiority in all adults age ≥18 years,…