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Hepatitis

Tenofovir alafenamide effectively treats HBV, no virologic resistance

Treatment with tenofovir alafenamide was as effective in suppressing hepatitis B replication as tenofovir disoproxil fumarate with no virologic resistance, according to recently published data on two 96-week trials. “Tenofovir…

Insulin resistance in HCV may be reversed with DAAs

Hepatitis C (HCV) is associated with insulin resistance, and elimination of the virus may help re-establish glycemic control in affected patients, according to a prospective case-control study published in the…

Elbasvir/grazoprevir plus ribavirin improves SVR in certain HCV genotypes

Elbasvir/grazoprevir (EBR/GZR) with or without ribavirin (RBV) appears to be tolerable and effective for achieving a sustained virologic response (SVR) at 12 weeks in certain genotype hepatitis C (HCV) infections,…

Smoking reduces survival after liver cancer diagnosis for people with viral hepatitis

People with viral hepatitis who smoked were three times more likely to die after being diagnosed with liver cancer (hepatocellular carcinoma, HCC), according to a study of Swiss patients published…

Injection drug users benefit from hepatitis C treatment

Since the emergence of costly direct-acting antiviral drugs, much controversy has surrounded the issue of which patients with hepatitis C virus (HCV) should receive treatment. Due to the high costs…

First chronic hepatitis B patient dosed in China in a Phase 1 trial of T101 (Transgene’s TG1050 technology)

STRASBOURG, France, January 17, 2018: Transgene (Paris:TNG) (Euronext Paris: TNG), a biotech company that designs and develops virus-based immunotherapies, announces that the first patient has been dosed in a Phase 1…

Hepatitis C treatment highly effective in harder-to-treat HIV coinfected patients, Spanish real-life study shows

Hepatitis C virus (HCV) treatment using direct-acting agents (DAAs) is highly effective and safe in harder-to-treat HIV co-infected patients, Spanish researchers report in AIDS. A sustained virological response (SVR), or…

Hepatitis A vaccines effective in high-risk populations during outbreak

Two-dose hepatitis A vaccination was an effective preventive measure among HIV-positive individuals, including a high study population of men who have sex with men, during an ongoing outbreak of acute…

Serological method could replace molecular for HCV testing

Serologic detection of hepatitis C virus antigen (HCV-Ag) could replace the previous detection standard of molecular HCV-RNA in the era of direct-acting antivirals (DAAs), as DAA effectiveness in treating HCV…

Epidemiological update: hepatitis A outbreak in the EU/EEA mostly affecting MSM

Since the last epidemiological update on this multi-country hepatitis A outbreak published on 29 September 2017, 22 EU/EEA countries (Austria, Belgium, Croatia, the Czech Republic, Denmark, Estonia, Finland, France, Germany,…

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