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Cure

Abivax releases positive top line data from ABX464-005 phase 2a study in HIV infection

-- Extended dosing with ABX464 observed to be safe and well-tolerated. -- Decrease in Total HIV DNA in blood observed with longer treatment. -- For the first time, HIV DNA…

What’s the fuss about a functional cure?

A cautious overview of the Hong Kong study by Miranda Smith A recent study from researchers in Hong Kong has got the world’s media talking about a functional cure for HIV.…

EHVA: a clinical trial for therapeutic vaccination for HIV is about to start

Today and tomorrow EATG is attending the European HIV Vaccine Alliance (EHVA) consortium meeting in Barcelona. The EATG is one of the 39 partners of the consortium that aims to develop…

Strategies for a cure

Three researchers talk with Positively Aware editor Jeff Berry about ongoing HIV cure research within the ACTG, treatment interruptions, and when we might see a cure. Read the full interview…

T cells alone are sufficient to establish and maintain HIV infection in the brain

These results indicate that T cells in the brain may be an important reservoir for HIV in patients that should be targeted by HIV cure approaches. CHAPEL HILL, NC, June…

Discovery of how HIV hedges its bets opens the door to new therapies

Scientists at Gladstone reveal how the virus decides between fates SAN FRANCISCO, CA, May 10, 2018 — A stem cell is one with infinite possibilities. So, for decades, scientists have…

Study challenges ‘shock and kill’ approach to eliminating HIV

Researchers have provided new insight into the cellular processes behind the 'shock and kill' approach to curing HIV, which they say challenges the effectiveness of the treatment. Their study, published…

Gene editing holds promise for shrinking HIV ‘reservoir’

Study mimicking Timothy Ray Brown’s HIV-resistant mutation led to fewer latently infected cells — a key step toward driving the virus into remission without the need for antivirals. By transplanting…

Gene-edited stem cells show promise against HIV in non-human primates

Edited cells reduce size of 'viral reservoirs' that could reactivate to produce more virus copies Gene editing of bone marrow stem cells in pigtail macaques infected with simian/human immunodeficiency virus…

Top HIV cure research team refutes major recent results on how to identify HIV persistence

Collaborative effort sets the record straight on the use of CD32 as a biomarker to measure HIV reservoirs. PHILADELPHIA — (April 18, 2018) — An international team focused on HIV…