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Cure

Researchers create molecule that could ‘kick and kill’ HIV

In lab animals, a particle developed by UCLA, Stanford, NIH scientists awakens dormant virus cells and then knocks them out Current anti-AIDS drugs are highly effective at making HIV undetectable…

Study quantifies scope of HIV ‘reservoir’ in infected people and points to potential curative strategies

MINNEAPOLIS, October 3, 2017 – A new study in the journal Nature Medicine suggests current antiretroviral therapies for the treatment of HIV infection are not making it into the tissues…

ABIVAX’s ABX464 reduces HIV reservoir in blood in second Phase 2a clinical trial

ABX464 first ever drug candidate to show statistically significant (p<0.01) reduction in HIV viral reservoir PARIS, Sept. 28, 2017 7:30 a.m. CEST – ABIVAX (Euronext Paris: FR0012333284 – ABVX), an innovative…

The Campbell Foundation awards grant to develop gene editing tool to destroy latent HIV cells in lymph nodes

Sept. 26, 2017 – FORT LAUDERDALE, FL –  The Campbell Foundation, a nonprofit organization dedicated to funding HIV/AIDS research, has awarded an $80,000 grant to Kristine Yoder, PhD, to develop…

Synthetic molecule ‘kicks and kills’ some persistent HIV in mice

New compound shows early promise as potential treatment for dormant HIV infection Scientists have designed a synthetic molecule that can reactivate dormant human immunodeficiency virus (HIV) in mice and lead…

Researchers find a way to reduce HIV replication in the gastrointestinal tract

Researchers at the Université de Montréal Hospital Research Centre (CRCHUM) have discovered a way to slow viral replication in the gastrointestinal tract of people infected by HIV-AIDS. This advance, published…

ABIVAX: First patient dosed in three-month cohort of Phase 2a study of oral ABX464 in HIV-suppressed patients

Trial will evaluate effects of ABX464 on HIV reservoirs in gut tissue and blood Study measures response rate over time PARIS, Sept. 18th, 2017 at 8 a.m. CEST – ABIVAX…

Is it ethical to take people off HIV meds for cure research?

Cure studies typically require a temporary break in HIV treatment, often with little promise of a personal benefit to the participant. In recent years, researchers have firmly established that people…

HIV cure-focused Excision BioTherapeutics secures $10 million in seed funding led by ARTIS Ventures

Gene editing leader developing therapeutics for the eradication of HIV moves toward human trials Philadelphia, September 6, 2017 -- Excision BioTherapeutics, a life science company focused on the development and…

New knowledge on how HIV beats the body’s early immune response

Research effort to find an elusive cure for HIV In an important step towards eradicating HIV-associated viral reservoirs, researchers at Sydney's Westmead Institute for Medical Research have identified how the…