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In unique case, Australian man appears to have cleared his HIV infection

Subject had an unusual combination of factors inhibiting HIV replication Researchers in Sydney, Australia have identified a patient who appears to have spontaneously cleared his own HIV infection without any…

Is it safe to alter the CCR5 receptor? And how will this influence HIV cure studies?

The HIV cure effort suffered a potential setback this week, as researchers reported an association between having two copies of the CCR5-∆32 mutation and shorter survival. Read the full blog post…

University of Minnesota research team works to eradicate HIV with natural killer cells

MINNEAPOLIS, April 29, 2019 -- A collaborative research team at the University of Minnesota has used Tri-specific killer engagers (TriKE) to target HIV-infected cells in preclinical testing. The team, led by Jeffrey Miller, MD, Deputy…

CROI 2019: Monoclonal antibody may lead to long-term viral load reduction

An experimental monoclonal antibody called PGT121 led to viral suppression that lasted for up to six months in HIV-positive people who started with a low viral load, according to results…

Immunotherapy kicks, kills HIV by exploiting a common virus

PITTSBURGH, April 3, 2019 – In a first on the quest to cure HIV, University of Pittsburgh Graduate School of Public Health scientists report today in EBioMedicine that they’ve developed an all-in-one immunotherapy approach that…

Science issues concern about HIV remission monkey study

The journal Science is warning readers that an article it published on a much-hyped potential HIV remission approach didn't include all the facts. In a so-called "editorial expression of concern"…

Curing HIV just got more complicated. Can CRISPR help?

SEATTLE, WASHINGTON — Antiretroviral (ARV) drugs have turned HIV infection from a death sentence to a chronic condition. In most people the drugs routinely tamp HIV levels so low that…

HIV i-Base: HTB, first reports from CROI 2019; Fit for Purpose report 2019 released

HIV Treatment Bulletin (HTB) is a community publication produced by HIV i-Base. This edition of HTB includes the first reports from CROI 2019, with additional reports following in subsequent issues.…

CROI 2019: ‘Molecular scissors’ successfully remove HIV genes from all tissues in infected monkeys

The top story from the Conference on Retroviruses and Opportunistic Infections (CROI 2019) in Seattle this week has been a likely second HIV cure. However, the cure involved an expensive…

CROI 2019: Viral reservoir can explain persistent low level viraemia with good adherence on ART

The dynamics of HIV proliferation in the viral reservoir might be the explanation for why viral load fails to become undetectable, especially when adherence is good. Such cases are often…

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