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Cure

Science issues concern about HIV remission monkey study

The journal Science is warning readers that an article it published on a much-hyped potential HIV remission approach didn't include all the facts. In a so-called "editorial expression of concern"…

Curing HIV just got more complicated. Can CRISPR help?

SEATTLE, WASHINGTON — Antiretroviral (ARV) drugs have turned HIV infection from a death sentence to a chronic condition. In most people the drugs routinely tamp HIV levels so low that…

HIV i-Base: HTB, first reports from CROI 2019; Fit for Purpose report 2019 released

HIV Treatment Bulletin (HTB) is a community publication produced by HIV i-Base. This edition of HTB includes the first reports from CROI 2019, with additional reports following in subsequent issues.…

CROI 2019: ‘Molecular scissors’ successfully remove HIV genes from all tissues in infected monkeys

The top story from the Conference on Retroviruses and Opportunistic Infections (CROI 2019) in Seattle this week has been a likely second HIV cure. However, the cure involved an expensive…

CROI 2019: Viral reservoir can explain persistent low level viraemia with good adherence on ART

The dynamics of HIV proliferation in the viral reservoir might be the explanation for why viral load fails to become undetectable, especially when adherence is good. Such cases are often…

CROI 2019: London patient in long-term HIV remission after stem cell transplant

A London man has no remaining detectable HIV a year and a half after undergoing a bone marrow stem cell transplant to treat lymphoma, researchers are reporting this week at…

First evidence of HIV reservoirs in macrophages

Basic scientists in France have recently discovered that macrophages located in urethral tissue can contribute to cellular HIV reservoirs, and that the quantity of these specific immune cells is surprisingly…

Finding clues to a functional HIV cure

Mason researcher helps identify a T cell marker that could help lead to improved treatment for HIV, cancer patients. George Mason University’s Yuntao Wu is the lead scientist on a…

Two new types of cell therapy could target reservoir cells and permanently stop HIV infection

Two studies published last month described promising new approaches which could stop HIV infecting cells. They could either eliminate or permanently suppress the activity of the so-called ‘reservoir’ cells which…

Scientists develop tool to measure success of HIV cure strategies

Scientists funded by the National Institutes of Health have developed a new assay to accurately and easily count the cells that comprise the HIV reservoir, the stubborn obstacle to an…

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