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Comorbidities

Adolescents with perinatally-acquired HIV are not at increased risk of anxiety, depression

Adolescents and Adults Living with Perinatal HIV (AALPHI) is an ongoing study in the United Kingdom that follows a cohort of young people with perinatally-acquired HIV (PHIV) and a control…

Study suggests that understanding chronic pain can help patients manage it better

People living with HIV/AIDS have higher rates of chronic pain than the general population does, mainly because of neuropathy but also partly because people with HIV are largely an aging…

Renal safety profile of triple DAA therapy in HIV/HCV coinfection examined

Ombitasvir/paritaprevir/ritonavir plus dasabuvir has a good renal safety profile in patients coinfected with HIV/hepatitis C, according to results published in PLoS ONE. The study included 144 patients coinfected with HIV…

CROI 2018: Research sheds more light on cardiovascular risk in people with HIV

People with HIV are more likely to develop cardiovascular conditions, including atherosclerosis and peripheral artery disease, than their HIV-negative counterparts, researchers reported at the 25th Conference on Retroviruses and Opportunistic…

Are current CVD risk prediction algorithms applicable in HIV?

Commonly applied cardiovascular disease (CVD) risk prediction functions, consisting of a composite of various risk factors associated with CVD development, are currently inadequate for estimating heart disease risk in men…

HIV and neurocognitive disorders: looking for drugs that decrease inflammation

Up to half of people living with HIV (PLWH) experience HIV-associated neurocognitive disorders (HAND), a neurological manifestation of HIV-1 infection. HAND appears to manifest pursuant to persistent central nervous system…

CATIE: February 2018 issue of TreatmentUpdate now online

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 225: Inflammation, HIV and marijuana, February 2018 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-225/inflammation-hiv-and-marijuana

Type 2 diabetes prevalence and its risk factors in HIV

A cross-sectional study Abstract Background Type 2 diabetes (T2D) has a reported greater prevalence and poorer treatment outcomes in people living with HIV (PLWH) than comparable HIV-uninfected cohorts. We conducted…

CROI 2018: NATAP reports

Conference on Retroviruses and Opportunistic Infections (CROI), 4-7 March 2018, Boston, Massachusetts, USA Multiple low doses of nucleoside MK-8591 strong in healthy volunteers Integrase inhibitor penetration generally worse in lymphoid…

CROI 2018: Mental health, a crucial component to ending HIV epidemic

At the 25th Conference on Retroviruses and Opportunistic Infections, Robert Remien, PhD, stressed in his presentation that addressing mental health is a critical component to ending the HIV epidemic and…