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Basic science

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of…

Ragon Institute study identifies viral peptides critical to natural HIV control

T-cell targeting of essential amino acids may underlie spontaneous HIV suppression, define path to a vaccine Investigators at the Ragon Institute of MGH, MIT and Harvard have used a novel approach…

Designer drugs to inhibit hepatitis A virus

Structure-based drug design revealed that a compound previously investigated for the treatment of head-and-neck cancer could function as a lead compound for the development of drugs to treat hepatitis A…

University of Minnesota research team works to eradicate HIV with natural killer cells

MINNEAPOLIS, April 29, 2019 -- A collaborative research team at the University of Minnesota has used Tri-specific killer engagers (TriKE) to target HIV-infected cells in preclinical testing. The team, led by Jeffrey Miller, MD, Deputy…

Mymetics receives HIV vaccine funding from the NIH

- Funding to prepare Mymetics' cold chain independent needle free mucosal virosome HIV vaccine candidate for clinical trials - Collaboration with Texas Biomedical Research Institute and University of Louisiana at…

How the hepatitis B virus establishes persistent infection

New research sheds light on how a hepatitis B viral protein stimulates the expansion of immune cells that impair antiviral responses, according to a study published April 18 in the…

Researchers identify how hepatitis A virus causes liver injury

CHAPEL HILL, NC – Hepatitis researchers have long thought that immune cells – sent to attack virus-infected cells in the liver – cause the acute liver injury associated with hepatitis…

Researchers identify how liver cells protect against viral attacks

Results have implications for cellular responses to hepatitis, dengue and Zika Chapel Hill, NC – Liver cells have an innate resistance to RNA viral infections like hepatitis A, dengue and Zika…

New imaging reveals previously unseen vulnerabilities of HIV

Breakthrough opens new paths to fight against the deadly virus BOSTON, MONTREAL, and MELBOURNE, Australia (April 10, 2019, 11 a.m. E.DT.) -- Imagine that HIV is a sealed tin can:…

Scientists find another way HIV can hide from vaccines

A Yale-led team has discovered yet another molecular trick HIV uses to survive immune system attacks, a finding that may influence efforts to develop an effective vaccine against HIV/AIDS. The…

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