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Basic science

Swift gene-editing method may revolutionize treatments for cancer and infectious diseases

Scientists report that they have discovered a way to tweak genes in the body’s immune cells by using electrical fields. For the first time, scientists have found a way to…

Gammaherpesviruses linked to tumors in macaques with simian immunodeficiency virus

Future macaque research could help clarify viruses' roles in cancer development in people with HIV Viruses known as gammaherpesviruses may raise the risk of cancer in macaques infected with Simian…

Breakthrough study shows how HIV is shielded from immune attack

A UNSW study has shown for the first time how HIV hijacks a host molecule to strengthen its protective shell and shield itself from attack. The findings have implications for…

A “super” receptor that helps kill HIV infected cells

While treatments for HIV mean that the disease is no longer largely fatal, the world still lacks a true therapy that can eradicate the virus across a globally – and…

Active HIV in large white blood cells may drive cognitive impairment in infected mice

Study surfaces new evidence of an important role for macrophages in HIV-related cognitive impairment Macrophages, large white blood cells that engulf and destroy potential pathogens, harbor active viral reserves that…

Discovery reveals how cells try to control levels of key HIV protein

Salk scientists uncover potential new targets for antiviral drugs using novel laboratory method LA JOLLA May 31, 2018—One of the many challenges in treating HIV is that the virus can…

Unlocking the secrets of HIV’s persistence

Thanks to advances in the development of anti-retroviral therapy (ART), patients with HIV are living longer than ever before. And yet, even in patients on very effective, long-term ART, HIV…

Genome editing method targets AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected…

Different diseases elicit distinct sets of exhausted T cells

Epigenomics survey of human immune cells has implications for fighting chronic infections, autoimmunity, and cancer The battle between the human immune system and long-term, persisting infections and other chronic diseases…

Discovery of how HIV hedges its bets opens the door to new therapies

Scientists at Gladstone reveal how the virus decides between fates SAN FRANCISCO, CA, May 10, 2018 — A stem cell is one with infinite possibilities. So, for decades, scientists have…

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