What is NEAT?

NEAT is a network of Excellence funded by the European Commission. Its mission is to strengthen European HIV clinical research capacity.

The main deliverables of NEAT are centered around clinical research (the NEAT001/ANRS 143 HIV clinical trial and its substudies, the NEAT HepC/HIV Cohort Network, intergration grants etc.) and training and education activities.

NEAT Mission is to:

  • strengthen the research capacity throughout Europe by building a network for clinical therapeutic trials in HIV in order to optimize the management of HIV;
  • define optimal strategies for management of HIV infection and guide the implementation of optimal interventions;
  • improve coherence, complementarities and integration and develop a common research programme in HIV research;
  • spread excellence through training programmes, mobility programmes, and informative programmes (including public events, conferences, website);
  • bring together the existing but dispersed critical mass of researchers (more than 200 scientists) and expertise in Europe from leading Institutions and Organisations (5 National Agencies, 2 established consortia, 16 leading clinical Institutions and 1 European Patient Association);
  • integrate leading HIV/AIDS research Institutions and Clinical Centres through a coherent, multidisciplinary and durable research programme;
  • tackle fragmentation and strengthen excellence by creating a Clinical Trial Platform to improve the efficacy and coherence of ongoing HIV/AIDS clinical research in Europe;
  • design the roadmap for a durable restructuring and reshaping of the way research is carried out in Europe to achieve a desired level of integration, in the medium/long term;
  • significantly increase the quality and ambitions of existing research in order to affirm Europe’s leadership in the field;
  • promote quality and excellence through the establishment of a PhD and post doctoral programme to train young scientists.

NEAT Structure

NEAT is currently composed of 40 “core” Partner Institutions, located in 16 European Countries (including the major National AIDS Research Agencies), with over 450 researchers, plus 357 affiliated centres. It can easily be understood that the coordination of such a huge and complex group of researchers needs, at the same time, strong guidance and management flexibility.

As decided by the NEAT Steering Committee, also following the advice of the European Commission reviews, the future activities of NEAT should be, from now on, focused on four major areas: 1. Network functioning; 2. Clinical research, particularly on randomized clinical trials; 3. Integration, which may be achieved through small, intensive cross-partner/cross-country clinical studies; 4. Education and Training, focused on clinical research training.

As a consequence, the previous 14 Work Packages have been regrouped into four new Work Packages. This revision of NEAT structure will allow not only a better understanding of the most important objectives of NEAT, but will facilitate and make more understandable the reporting of the activities.

WP 1) - Network functioning

This new workpackage includes the activities of the following initial Work Packages: Management, Fundraising, Networking, Information Technology, Quality.

WP 2) - Clinical Research

This new workpackage includes the activities of the following initial Work Packages: Clinical research, Trial management, Trial design and analysis, Community and Ethics, Virology, Immunology, Regulatory, Fundraising, IT, Quality + Individual partner institutions members of Neat Trials Committees and Clinical external institutions who will enrol patients into the trials.

WP 3) - Integration

This new workpackage includes the activities previously distributed in different Work Packages, and now distributed almost through all partner institutions through Integration Grants and Exchange Fellowships.

WP 4) - Education and Training

This new workpackage includes the activities of the initial Work Package, but now is spread across almost all partner institutions, particularly those involved in trial management for Trial Investigators Training, and in for the Community/patients involvement/sensibilization.

The new operational structure is presented below with a responsible partner institution representative identified for each overarching activity.

(Approved in the SC meeting held 12th of May 2009 and re-confirmed in the SC meeting held 18th of Sept 2009)

Steering Committee (11 members) and General Assembly

ISS NEAT management team

WP 1

Network functioning

Overall responsibility: ISS/Vella

WP 2

Clinical research

Overall responsibility: SSAT/Pozniak

WP 3

Integration

Overall responsibility:

CI-MHH/Schmidt

APHP/Katlama

WP 4

Education and Training

Overall responsibility: PENTA/Giaquinto

EATG/Dedes

Activities:

Management & Governance, Fundraising, External networking, Public Website and IT, Quality

Activities:

NEAT 001/ANRS 143 trial; Hepatitis cohort;

Other clinical trial studies

Activities:

Integration Grants, Exchange Programmes

Activities:

Courses & Training, PhD, Master programmes

All Partner Institutions

Steering Committee Members

Abdel Babiker
Nikos Dedes
Jean Francois Delfraissy
Stephan De Wit
Josè Gatell
Andrzej Horban
Christine Katlama
Anton Pozniak
Jurgen Rockstroh
Reinhold Ernst Schmidt
Stefano Vella
Patrick Yeni

Scientific Advisory Committee Members

Scott Hammer

Connie Benson

David Cooper

Pedro Cahn

Mauro Schekter

Paula Munderi

Mark Wainberg

Patrik Yeni

Governance Advisory Committee Members

Julio Montaner

Michel Kazatchkine

Kevin de Cock

Catherine Peckham

Peter Reiss

NEAT Partners

N.

Institution

Country

Acronym

Team Leader

1

Istituto Superiore di Sanità - ISS

Italy

ISS

Stefano Vella

2

Agence National de Recherche sur le SIDA et les Hepatites Virales (ANRS)

France

ANRS

Jean François Delfraissy

3

Competence Network HN/AIDS
Ruihz Universitat Bochum

Germany

CN-AIDS-D

Norbert Brockmeyer

4

Medical Research Council - MRC

United Kingdom

MRC

Abdel Babiker

5

Academisch Medisch Centrum

Netherlands

AMC

Joep Lange

6

National University of Ireland
University College Dublin - School of Medicine and Medical Sciences

Ireland

UCD

William Powderly

7

University of Lisbon,
Facultade de Medicina de Lisboa

Portugal

FML

Francisco Antunes

8

Hospital Clinic i Provincial de Barcelona

Spain

HCPB

Josè M. Gatell

9

Fundacio Lluita contra la SIDA

Spain

FLS

Bonaventura Clotet

10

Hospital Carlos III - Service of Infectious Diseases

Spain

HCIII

Vicente Soriano

11

Hospital La Paz HIV-UNIT

Spain

HULP

Jose Arribas

12

Saint Pierre University Hospital HSP Department of Infectious Diseases

Belgium

HSP

Nathan Clumeck

13

Wojewodzki Szpital Zakazny WSZ AIDS - Diagnosis and Therapy Center

Poland

WSZ

Andrzej Horban

14

University Hospital Plzen CZ FZ
Department of Infectious Diseases - AIDS Center

Czech Republic

FN Plzen

Dalibor Sedlacek

15

5th Dept. of Medicine - Saint Laszlo Hospital

Hungary

SLH

Denes Banhegy
(Dr. Újhelyi Eszter )

16

Karolinska Institut, Stockholm

Sweden

KI

Anders Sònnerborg

18

Assistance Publique - Hopitaux de Paris

France

AP-HP

Jean Michel Molina, Christine Katlama, Patrick Yeni, Yves Levy, Brigitte Autran

19

Centre Hospitalier Universitaire de Nantes Dep. of Infectious Diseases - HIV Clinical Research Unit

France

UHN

François Raffi

20

Universitè PARIS 7 - Denis Diderot

France

UP7DD

Françoise Brun Vezinet

21

University of Bonn - Department of Medicine

Germany

UKB

Jùrgen Rockstroh

22

Abteilung Klinische Immunologie Medizinische Hochschule Hannover

Germany

CI-MHH

Reinholdt Ernst Schmidt

23

Hospital of the Johann Wolfang Goethe University

Germany

Frank- HIV

Cristoph Stephan
Hans Reinhard Brodt

24

National Institute for Infectious Diseases “L. Spallanzani” (IRCCS)

Italy

INMI

Andrea Antinori

25

Universita degli Studi di Brescia - Institute of Infectious and tropical diseases

Italy

UNI-BS

Gianpiero Carosi

26

Fondazione Centro San Raffaele del Monte Tabor

Italy

FCSR-CSL

Giuseppe Tambussi

27

Università degli Studi di Roma Tor Vergata Dept. of Public Health

Italy

UTV

Massimo Andreoni

28

Università degli studi di Milano – Dept. of Clinical Sciences “L. Sacco”

Italy

UNIMI

Massimo Galli

29

St. Stephens AIDS Trust - Dep. of HIV

United Kingdom

SSAT

Anton Pozniak

30

Royal Free and University College Medical School of UCL - Dep. of Primary Care and Population Sciences

United Kingdom

UCL

Andrew Phillips

31

University Medical Center Utrecht - Department of Virology

Netherlands

UMC

Rob Schuurman

32

International Antiviral Therapy Evaluation Center

Netherlands

IATEC

Remko Van Leeuwen

33

Sozialmedizinischess Zentrum Baumgartner H-HE-Otto Wagner Spital Mit Pflegezentrum

Austria

OWS

Brigitte Schmied

34

Center Hospitalier Universitaire (CHUV) - SWISS HIV Cohort Study

Switzerland

SCHS

Patrick Francioli, Manuel Battegay

35

PENTA for the treatment and care of children with HIV and related diseases - Onlus

Italy

PENTA

Carlo Giaquinto

36

European AIDS Treatment Group

Internatl.

EATG

Nikos Dedes

37

Cineca, Consorzio Interuniversitario

Italy

CINECA

Marisa De Rosa

Amended Partners since 1st of February 2008

38

Universite Victor Segalen Bordeaux 2

France

UB2

Geneviève Chène

39

Institut National de la Sante et de la Recherche Medicale

France

INSERM

J.P. Aboulker

40

Erasmus University Medical Center Rotterdam, Dept of Virology

The Netherlands

ERASMUS

Charles Boucher

41

University of Copenhagen

Denmark

CHIP

Jesper Grarup, Jens Lundgren

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