Thematic ECAB on Tuberculosis (March 26-27, 2010, Brussels)

Report of the meeting:

ECAB is the working group from EATG dealing with clinical research and science projects for HIV/AIDS and its co-infections. ECAB meets several times a year with the pharmaceutical industry where under confidentiality new advances in drug development and access to treatment in the WHO-Euro region are being discussed with patient advocate experts in clinical research and access issues from the whole region.

Since 2007, ECAB has expended its portfolio of activities and has started addressing co-infection issues as well. Several ECAB meetings and thematic workshops have been organized with a specific focus on for instance development of anti-Hepatitis C drugs for HCV/HIV co-infected populations (for further information).

ECAB is now developing further its research and science agenda looking into clinical development and access to TB treatment for HIV & TB co-infected patients, and the second thematic ECAB meeting on TB and HIV co-infection was held on March 26-27 2010 in Brussels, Belgium.

The main objectives and outcomes of the meeting were to serve as training for the European patient Community on TB & HIV co-infection clinical issues and to help building a TB/HIV community advocacy agenda in the WHO-Euro region.

This workshop was attended by around 30 participants: patient advocates from EATG/ECAB, representatives of civil society institutions involved in TB Clinical issues (TAG, TB Alert, TB Action Group...), clinical researchers and international organization representatives active in the TB research field (WHO, StopTB partnership...).

The organizers: Laure Sonnier (EATG), Wim Vandevelde (EATG) and Claire Wingfield (TAG)

Agenda & Presentations

The speakers: Claire Wingfield (TAG), Uli Fruth (WHO-Stop TB), Smiljka De Lussigny and Andrei Dadu (WHO-Euro), Dmytro Donchuk (MSF Kyrgystan), Martina Casenghi (MSF), Soumya Swaminathan (WHO Geneva), Ruth McNerney (LSHTM), Stefan Stojanovik (EATG).

Basics of TB by Claire Wingfield (TAG)

Current treatments and diagnostics for TB by Claire Wingfield (TAG)

Epidemiology of TB and coinfection with HIV in the WHO-Euro region by Andrei Dadu andSmiljka de Lussigny (WHO-Euro)

Trends in TB R&D funding by Claire Wingfield (TAG)

Update on TB pipeline- Treatment by Martina Casenghi (MSF)

The specificity of Clinical Trials design for TB drugs by Soumya Swaminathan (WHO Geneva)

Update on TB pipeline- Vaccines by Uli Fruth (WHO-Stop TB)

Update on TB pipeline- Diagnostics by Ruth Mc Nerney (LSHTM)

TB and Human Rights by Claire Wingfield (TAG)Talked prepared with the support of Diana Weil (WHO) and Alasdair Reid (UNAIDS)

TB in HIV/TB patients using drugs in Eastern Europe by Dmytro Donchuk (MSF - Kyrgyzstan)

TB management & programming in Europe, TB/HIV collaborative activities and the involvement of the GFATM by Stefan Stojanovik (EATG BOD)

Backgrounds materials

WHO-Stop TB partnership

Summary of the TB/HIV Research Frontiers meeting (including IAS 2009 and CROI 2010)

http://www.stoptb.org/wg/tb_hiv/meetingsevents.asp

WHO

Interim policy on collaborative TB/HIV activities

http://www.who.int/tb/publications/tbhiv_interim_policy/en/

Treatment Action Group (TAG)

TB/HIV project

http://www.stoptb.org/wg/tb_hiv/meetingsevents.asp

TB/HIV at CROI 2010

Oral Abstracts: TB Prevention and Treatment and Complications of HIV and ART - Feb 18, 2010 9:30 AM

http://www.retroconference.org/2010/data/files/webcast_2010.htm

Oral Abstracts: Treatment Outcomes in Women and Children - Feb 19, 2010 9:30 AM

http://www.retroconference.org/2010/data/files/webcast_2010.htm

Symposium: The Future of HIV Therapeutic Research—The Treatment Agenda- Feb 19, 2010 4:00 PM

Future Directions in HIV/TB Research
Diane Havlir -Univ of California, San Francisco, US

http://www.retroconference.org/2010/data/files/webcast_2010.htm

MSF- Access campaign

http://www.msfaccess.org/main/tuberculosis/

http://www.msfaccess.org/resources/key-publications/key-publication-detail/?tx_ttnews[tt_news]=1597&cHash=8651ef9c32

TB Alert

http://www.tbalert.org/

Understanding Tuberculosis

http://www.understandingtb.org/default.html

TB action group

http://tbactiongroup.ning.com/

http://www.who.int/tb/people_and_communities/involvement/en/index.html

http://www.who.int/tb/people_and_communities/involvement/resources/en/index.html

1. patient charter http://www.who.int/tb/publications/2006/istc/en/index.html

2. berlin declaration http://www.euro.who.int/Document/E90833.pdf

http://www.euro.who.int/tuberculosis/TBForum/20070621_1

country spesific data on TB/HIV collaborative acctivities might be donwloated form the Global TB report web http://www.who.int/tb/publications/global_report/2009/update/en/index.html

M/XDR-TB global report http://www.who.int/tb/features_archive/world_tb_day_2010/en/index.html

StopTB strategy http://www.who.int/tb/strategy/en/index.html

A guide to monitoring and evaluation for collaborative TB/HIV activities http://whqlibdoc.who.int/publications/2009/9789241598194_eng.pdf

Policy guidelines for collaborative TB and HIV services for injecting and other drug users: an integrated approach http://www.who.int/tb/publications/2008/tbhiv_policy_guidelines_injecting_drugusers/en/index.html

Management of Tuberculosis and HIV Coinfection http://www.euro.who.int/document/SHA/e90840_chapter_4.pdf

Interim policy on collaborative TB/HIV activities http://www.who.int/tb/publications/tbhiv_interim_policy/en/index.html

For further information, please contact Laure Sonnier , Scientific Adviser.