Treatment

Treatment 08/02/2012

Conflicting data on bone fracture link to HIV meds

Whether specific drugs such as tenofovir increase the risk, reduce the risk, or have a variable effect over time remains unclear.

Treatment 08/02/2012

NeurogesX patch for HIV pain might be ineffective, FDA staff report says

The FDA is scheduled to decide whether to approve Qutenza by March 7. The agency doesn’t have to follow the advisory panel’s recommendation.

Treatment 08/02/2012

Salix Pharmaceuticals announces FDA granting of Priority Review designation for the crofelemer NDA for treatment of diarrhea in patients with HIV/AIDS on anti-retroviral therapy

The FDA grants a Priority Review designation to drugs offering major advances in treatment, or providing a treatment where no adequate therapy exists.

Treatment 08/02/2012

HIV severity may influence mental health and academic ability in HIV-positive teens

HIV severity is associated with the severity of some mental health problems and academic, cognitive, and social impairments in teens born with HIV.

Treatment 07/02/2012

Rise of cancer in developing countries ‘linked to HIV’ says specialist

At least 30% of the cancers in developing countries are related to infection but HIV has emerged as a single major factor in the recent accelerated burden of cancer.

Treatment 06/02/2012

Spinal cord stimulation effective for HIV neuropathy

Constant spinal cord stimulation delivered through a permanently implanted device can offer pain relief to patients with HIV-related polyneuropathy that is refractory to conservative treatment.

Treatment 06/02/2012

New BHIVA guidelines recommend discussion with all patients on potential of HIV treatment to protect sexual partners

Treatment should be offered in circumstances where patients are concerned about the risk of transmitting HIV to partners – even if they are not in a serodiscordant relationship at the time.

Treatment 02/02/2012

Isentress, Intelence, Prezista regimen goes the distance for HIV treatment veterans

In treatment-experienced patients, an antiretroviral regimen containing raltegravir, etravirine and darunavir/ritonavir shows high efficacy, with a good safety profile.

Treatment 01/02/2012

HIV care providers in US struggling to cope with rising patient numbers

There is an increased need to train more primary care providers in HIV care. Coordinated, national efforts are required to built infrastructure, increase access points, and enhance provider capabilities to help ensure that patients get quality HIV care.

Treatment 31/01/2012

California study underscores the need to reduce cancer risk

Among HIV-positive people the risk for some cancers is elevated, though in some cases low CD4+ counts play a role in intensifying susceptibility to cancer.

Treatment 29/01/2012

Head, neck cancer treatment of less benefit for HIV patients

Conventional therapy for head and neck cancer appeared more toxic and less effective for patients with co-existing HIV infection.

Treatment 26/01/2012

Early antiretrovirals boost immune response in HIV infants

Infants with perinatal HIV infection should start antiretroviral therapy before three months of age.

Treatment 25/01/2012

Virologic failure on rilpivirine may lead to broad NNRTI resistance

In the ECHO and THRIVE trials, 10% of the patients who received rilpivirine-based regimens experienced treatment failure. Nearly half of these patients developed resistance to multiple nonnucleoside reverse transcriptase inhibitors.

Treatment 24/01/2012

Gilead initiates Phase 2 clinical trial evaluating GS-7340, a low-dose novel prodrug of tenofovir for the treatment of HIV

Phase 2 study will examine GS-7340 as part of a new once-daily, single-tablet regimen.

Treatment 24/01/2012

Face fillers and dental work—caution needed

HIV-positive people who have facial implants should always remind their oral health care professionals, including dentists, hygienists and surgeons, about the presence of such implants prior to receiving any oral care.

Treatment 24/01/2012

Smoking cessation counselling and treatment during routine HIV care helps patients to quit

Smoking cessation should be a topic of discussion in any physician-patient contact.

Treatment 24/01/2012

English public health indicators to include late HIV diagnosis

The Department of Health this week announced the 66 ‘indicators’ with which the performance of the new public health system will be measured.

Treatment 20/01/2012

Viread causes greater loss of kidney function than Ziagen in low-weight people with HIV

People with HIV who are taking Viread, Truvada, or Atripla and have a low body weight should be monitored for loss of kidney function at least twice per year, particularly during their first year of treatment.

Treatment 20/01/2012

Can speeding up nevirapine clearance reduce the risk of resistance after PMTCT use?

In a bid to reduce the risk of nevirapine resistance after the use of single-dose nevirapine to prevent mother-to-child HIV transmission, several research groups are now experimenting with the use of drugs that can speed up the clearance of nevirapine from the mother’s bloodstream after giving birth.

Treatment 19/01/2012

U.S. Food and Drug Administration approves new formulations of Viread® for use by children living with HIV

Viread now available in an oral powder and three lower-strength tablets.

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