Basic Science

Basic Science 15/11/2008

Researchers identify toehold for HIV's assault on brain

Scientists have unraveled in unprecedented detail the cascade of events that go wrong in brain cells affected by HIV, a virus whose assault on the nervous system continues unabated despite antiviral medications that can keep the virus at bay for years in the rest of the body.

Basic Science 15/11/2008

Novel regulatory step during HIV replication

A previously unknown regulatory step during HIV replication provides a potentially valuable new target for HIV/AIDS therapy, report researchers at the Salk Institute for Biological Studies and the University of Wisconsin, Madison.

Basic Science 11/11/2008

Cells exhausted from fighting HIV infection can be rescued

Researchers at the University of Toronto and the University of California, San Francisco, have revealed new hope for HIV treatment with the discovery of a way to 'rescue' immune cells that are exhausted from fighting off HIV infection.

Basic Science 11/11/2008

Astragalus extract may strengthen immune response to HIV

An extract from a plant used in traditional Chinese medicine may help protect the genes of immune system cells and, as a result, enhance their ability to fight HIV.

Basic Science 10/11/2008

Souped-up immune cells catch even disguised HIV

Genetically engineered immune cells can spot the AIDS virus even when it tries to disguise itself, offering a potential new way to treat the incurable infection, researchers reported on Sunday.

Basic Science 07/11/2008

Researchers examining protein communication to prevent HIV

The goal of the research is to "find a way so HIV is not the dominant communicator among proteins."

Basic Science 30/10/2008

Researchers find new chemical key that could unlock hundreds of new antibiotics

With bacterial resistance growing researchers are keen to uncover as many new antibiotics as possible.

Basic Science 29/10/2008

Sangamo BioSciences presents data at ICAAC demonstrating 'in vivo' protection against HIV infection by CCR5-ZFN therapeutic

Preclinical animal data demonstrates selective survival advantage of ZFN-treated immune cells after HIV infection and reduced viral loads.

Basic Science 21/10/2008

Researchers identify novel type of antibody that potently inhibits HIV infection

This finding may provide insight into the development of new treatments against HIV and other viruses, hopefully in the not too distant future.

Basic Science 13/10/2008

Body's anti-HIV drug explained

Humans have a built-in weapon against HIV, but until recently no one knew how to unlock its potential.

Basic Science 02/10/2008

HIV's genetic 'flight plan' filed

Researchers here think they've teased out the "flight plan" HIV follows as it hijacks the host cellular machinery in early HIV infection.

Basic Science 01/10/2008

University of Missouri scientists ‘see’ how HIV matures into an infection

After improving the sensitivity of nuclear magnetic resonance, researchers actually watched the HIV-1 protease mature from an inactive form into an active infection.

Basic Science 26/09/2008

Scientists unmask key HIV protein, open door for more powerful AIDS drugs

New U-M discoveries on how HIV evades immune system could one day eliminate the need to take antiviral drugs for a lifetime.

Basic Science 23/09/2008

Relocation of gut bacteria linked to low CD4s

In some people living with HIV, bacteria normally contained within intestinal lymph nodes are relocated to the blood stream. This process is associated with a lack of increase in CD4 cells —even in people whose HIV viral load is undetectable.

Basic Science 22/09/2008

Why some primates, but not humans, can live with immunodeficiency viruses and not progress to AIDS

Key differences in immune system signaling and the production of specific immune regulatory molecules may explain why some primates are able to live with an immunodeficiency virus infection without progressing to AIDS-like illness, unlike other primate species that succumb to disease.

Basic Science 19/09/2008

Researchers invigorate 'exhausted' immune cells

In battles against chronic infections, the body's key immune cells often become exhausted and ineffective.

Basic Science 11/09/2008

New study building off Viral Genetics’ research aims to unlock the mysteries behind Lyme Disease and other immune based diseases including HIV/AIDS

Gift from undisclosed source will go towards study which researchers hope will reconcile long-standing debate over treatment of Lyme Disease.

Basic Science 10/09/2008

Altor BioScience licenses T-cell receptors targeting HIV and hepatitis C from Massachusetts General Hospital

The specific targeting to HIV-infected cells makes it possible for the first time to eliminate latent viral reservoirs, which cannot be achieved with currently available treatments.

Basic Science 04/09/2008

Roman Empire 'raised HIV threat'

The spread of the Roman Empire through Europe could help explain why those living in its former colonies are more vulnerable to HIV.

Basic Science 04/09/2008

Gene may hold key to neutralizing HIV: U.S. study

The AIDS virus is especially hard to fight because few people develop antibodies to neutralize it, but researchers have found an immunity gene that may offer a new way to fight back.

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