Basic Science
Basic Science 21/04/2010
Study identifies the source of inherent noise in HIV gene expression
New research identifies a molecular mechanism that the human immunodeficiency virus (HIV) appears to utilize for generating random fluctuations called "noise" in its gene expression.
Basic Science 11/04/2010
HIV disrupts mucosal barriers
Exposure to HIV can directly disrupt cellular barriers whose function is to keep pathogens out, researchers said.
Basic Science 11/04/2010
New therapy shows potential as an anti-HIV medication
A new antibody-based therapy prevents HIV from infecting CD4 cells and could become a potent antiviral treatment.
Basic Science 09/04/2010
More clues emerge on how HIV infects women
Virus can invade after breaking down the protective barrier in women's reproductive tract, study finds.
Basic Science 09/04/2010
Protein find may help fight HIV
A discovery about the way HIV attacks the immune system could pave the way for the development of new treatments, scientists said.
Basic Science 06/04/2010
Scientists find clues to how the body fights off HIV
Research on antibodies may aid vaccine development.
Basic Science 06/04/2010
Scientists provide first-ever glimpse of HIV protein structure
Scientists from the California Institute of Technology (Caltech) have provided the first-ever glimpse of the structure of a key protein-gp120-found on the surface of a specific subgroup of the human immunodeficiency virus, HIV-1.
Basic Science 05/04/2010
Researchers announce new HIV-silencing stem cell therapy
“This therapy would offer an alternative for HIV-infected patients that can no longer be treated with regular antivirals.”
Basic Science 28/03/2010
Argos Therapeutics presents new Phase 2a data on the impact of Arcelis™ HIV program on viral genetic diversity
Poster presented at Keystone Symposia Global Health Series HIV Vaccines meeting.
Basic Science 28/03/2010
Role Tregs play in therapeutic HIV vaccines
A special class of T cells may be limiting the effectiveness of therapeutic vaccines for HIV by slowing the immune system response too soon.
Basic Science 23/03/2010
Controlling HIV: Highly promising new compound developed
A compound that can inhibit the transfer of HIV from one cell to another has been developed by researchers at the Institut de Biologie Structurale Jean-Pierre Ebel (CNRS/Université Joseph Fourier/CEA).
Basic Science 15/03/2010
Chemical in bananas may prevent and treat HIV
This may lead to the development of inexpensive microbicides to prevent HIV transmission and, quite possibly, novel compounds to treat the disease.
Basic Science 09/03/2010
New study may lead to expansion of drug arsenal used to fight HIV
New study from Universite de Montreal and VGTI may lead to improved defences.
Basic Science 09/03/2010
HIV hides out in bone marrow cells
Another secret stash of the virus makes it that much harder to eliminate, scientists say.
Basic Science 05/03/2010
TLR's role in HIV-1 reactivation induced by periodontal pathogens
Increased bacterial growth and emergence of periodontopathogens or their products accompanying chronic oral inflammatory diseases could be risk modifiers for viral replication and transmission, systemic immune activation and AIDS progression in HIV-1 patients.
Basic Science 03/03/2010
LEDGF/p75 integrase inhibitors and capsid assembly inhibitors offer new approaches for blocking HIV replication
While the drug development pipeline is not as full as it has been in recent years, researchers continue to work on new approaches to antiretroviral therapy.
Basic Science 26/02/2010
Individuals who naturally lack CCR5 receptor have resistant to HIV
Researchers successfully removed CCR5 - a cell receptor to which HIV-1 binds for infection but which the human body does not need - from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.
Basic Science 25/02/2010
α-defensins1-3 may be potential prophylactic agents in treatment of HIV/AIDS
For the first time the increased α-defensins1-3 production by dendritic cells shows a slower progression of the infection.
Basic Science 20/02/2010
Gene therapy shows promise against HIV
Early findings suggest it could work, but application remains years away.
Basic Science 04/02/2010
New class of AIDS drug?
Two compounds lay foundation, help combat drug-resistant virus strains.
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