Basic Science
Basic Science 09/03/2010
New study may lead to expansion of drug arsenal used to fight HIV
New study from Universite de Montreal and VGTI may lead to improved defences.
Basic Science 09/03/2010
HIV hides out in bone marrow cells
Another secret stash of the virus makes it that much harder to eliminate, scientists say.
Basic Science 05/03/2010
TLR's role in HIV-1 reactivation induced by periodontal pathogens
Increased bacterial growth and emergence of periodontopathogens or their products accompanying chronic oral inflammatory diseases could be risk modifiers for viral replication and transmission, systemic immune activation and AIDS progression in HIV-1 patients.
Basic Science 03/03/2010
LEDGF/p75 integrase inhibitors and capsid assembly inhibitors offer new approaches for blocking HIV replication
While the drug development pipeline is not as full as it has been in recent years, researchers continue to work on new approaches to antiretroviral therapy.
Basic Science 26/02/2010
Individuals who naturally lack CCR5 receptor have resistant to HIV
Researchers successfully removed CCR5 - a cell receptor to which HIV-1 binds for infection but which the human body does not need - from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.
Basic Science 25/02/2010
α-defensins1-3 may be potential prophylactic agents in treatment of HIV/AIDS
For the first time the increased α-defensins1-3 production by dendritic cells shows a slower progression of the infection.
Basic Science 20/02/2010
Gene therapy shows promise against HIV
Early findings suggest it could work, but application remains years away.
Basic Science 04/02/2010
New class of AIDS drug?
Two compounds lay foundation, help combat drug-resistant virus strains.
Basic Science 02/02/2010
Study shows antiviral drugs could offer protection against HIV, Ebola, herpes and hepatitis C
Army Medical Research Institute of Infectious Diseases and Cornell University have teamed up to develop and test a broad-spectrum antiviral compound capable of stopping a wide range of highly dangerous viruses, including Ebola, HIV, hepatitis C virus, West Nile virus, Rift Valley fever virus and yellow fever virus, among others.
Basic Science 01/02/2010
Scientists say crack HIV/AIDS puzzle for drugs
Study solves puzzle that eluded scientists for 20 years; Finding should help development of new HIV/AIDS medicines; Allows scientists to see how Merck and Gilead drugs work.
Basic Science 31/01/2010
Findings could guide in developing more effective vaccines for HIV/AIDS and cancer
Scientists have identified a molecule that defines which cells are destined to become memory T cells just a few days after a viral infection begins. The finding could guide the development of more effective vaccines for challenging infections such as HIV/AIDS and also cancer.
Basic Science 13/01/2010
Update on HIV eradication
Developing the ability to eradicate established HIV infection requires a prolonged scientific commitment, further discoveries in the basic mechanisms of HIV persistence, the development of new model systems to test therapeutic approaches, and careful but innovative translational studies.
Basic Science 12/01/2010
Protein bits produced by unusual "reading" of HIV genome can induce immune responses
The information provided by these findings may prove useful during future HIV vaccine design efforts.
Basic Science 06/01/2010
Scientists discover anti-HIV molecule that may prevent infection
A team of American scientists has discovered a molecule that could block transmission of HIV, the virus that causes AIDS. Researchers say the preventive agent might someday be used in a topical cream to help prevent infection with the deadly virus.
Basic Science 17/12/2009
Immune system produces neutralizing antibodies capable of blocking HIV, says study
Scientists seeking to understand how to make an AIDS vaccine have found the cause of a major roadblock.
Basic Science 08/12/2009
UCLA researchers demonstrate that stem cells can be engineered to kill HIV
Innovative strategy could be effective against other chronic viral diseases.
Basic Science 07/12/2009
Comparative study on African monkeys may provide novel targets for AIDS therapy
Two studies published this month in the Journal of Clinical Investigation provide a significant advance in understanding how some species of monkeys such as sooty mangabeys and African green monkeys avoid AIDS when infected with SIV, the simian equivalent of HIV.
Basic Science 07/12/2009
Ancient HIV stowaway may hold clue to transmission
An HIV genetic stowaway that may have come from a related cat virus could help the AIDS virus transmit and replicate in people, U.S. researchers reported on Sunday.
Basic Science 02/12/2009
Reductionist model provides new insights on HIV infection
A team of researchers created a mouse that has key features of HIV infection without being infected with HIV.
Basic Science 02/12/2009
Mechanism blocking HIV-1 from entering cells identified
Publishing in PLoS Pathogens, researchers from the Kimmel Cancer Center at Jefferson have found a novel mechanism by which drugs block HIV-1 from entering host cells.
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