Basic Science
Basic Science 06/01/2012
Enzyme structure opens the door to HIV and Hepatitis C treatment: New study
Scientists have determined the structure of the enzyme endomannosidase, significantly advancing our understanding of how a group of devastating human viruses including HIV and Hepatitis C hijack human enzymes to reproduce and cause disease.
Basic Science 28/12/2011
HIV’s 'pathogenic landscape' research identifies new drug targets
Researchers believe they have succeeded in mapping every apparent physical interaction HIV makes with components of the immune system cells it infects, work they say should ultimately reveal new therapeutic and curative drugs.
Basic Science 23/12/2011
Researchers discover protein "key" that allows HIV to enter host cell nucleus
An international team of investigators has shown how the capsid of HIV-1 binds to a nuclear pore protein in host cells, enabling the virus to enter a cell's nucleus and inject its genetic material into the cell's chromosomes.
Basic Science 15/12/2011
Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C
Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion.
Basic Science 13/12/2011
Study describes new method that synthesizes novel anti-HIV protein
It can help in the development of a highly effective vaccine against HIV.
Basic Science 30/11/2011
Novel compound dissolves HIV on contact, also kills hepatitis C virus
Researchers discovered a small-molecule compound dubbed PD 404,182 that both inhibits HCV replication and destroys HIV on contact.
Basic Science 24/11/2011
NIH-led study advances HIV vaccine research
Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus.
Basic Science 08/11/2011
Study provides blueprint for design of new HIV drugs
Scientists have moved a step closer to understanding how one of our body's own proteins helps stop the human immunodeficiency virus (HIV-1) in its tracks.
Basic Science 05/11/2011
Building better antibodies can protect cells from HIV infection
These findings may contribute to development of more effective HIV vaccines in the future.
Basic Science 14/10/2011
Insight into how powerful anti-HIV antibody grabs hold of the virus
Researchers at The Scripps Research Institute have uncovered the surprising details of how a powerful anti-HIV antibody grabs hold of the virus.
Basic Science 23/09/2011
Synthetic lectins inhibit HIV from entering cells
Researchers have discovered a new class of compounds that stick to the sugary coating of the AIDS virus and inhibit it from infecting cells - an early step toward a new treatment to prevent sexual transmission of the virus.
Basic Science 20/09/2011
Dogfish shark chemical squalamine 'stops human viruses'
A chemical found in the dogfish shark could be a safe and potent weapon against human viruses, say scientists.
Basic Science 20/09/2011
Liposomes block HIV infection in early tests
Could engineered fatty particles help prevent AIDS?
Basic Science 20/09/2011
Scientists find way to "disarm" AIDS virus
Scientists have found a way to prevent HIV from damaging the immune system and say their discovery may offer a new approach to developing a vaccine against AIDS.
Basic Science 20/09/2011
Online gamers decipher 3D molecular structure that may help AIDS research
Cracking the enzyme provides new insights for the design of antiretroviral drugs.
Basic Science 15/09/2011
Unlocking blood-brain barrier may improve neurological treatment outcomes
Researchers have found a way to open and close the blood-brain barrier, which may allow for more effective treatment of a variety of brain-centered diseases and complications, such as those associated with HIV/AIDS.
Basic Science 14/09/2011
An immune system trained to kill cancer
Cancers may be vulnerable to a novel approach, which employs a disabled form of HIV-1 to carry cancer-fighting genes into the patients’ T-cells.
Basic Science 12/09/2011
Green-glowing cats are new tool in AIDS research
U.S. scientists have developed a strain of green-glowing cats with cells that resist infection from a virus that causes feline AIDS, a finding that may help prevent the disease in cats and advance AIDS research in people.
Basic Science 07/09/2011
New HIV vaccine approach targets desirable immune cells
Researchers have demonstrated an approach to HIV vaccine design that uses an altered form of HIV's outer coating or envelope protein.
Basic Science 27/08/2011
George Mason research team uncovers new factor in HIV infection
Building off previous findings, HIV researchers hope discovery will aid new therapies.
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