Treatment

Treatment 09/03/2010

Elvitegravir helpful in resistant HIV

In previously treated HIV patients, the integrase inhibitor elvitegravir suppresses the virus at least as well as ritonavir-boosted protease inhibitors, and at certain doses is actually superior, researchers report in the March 15th issue of the Journal of Infectious Diseases.

Treatment 09/03/2010

Hospital admissions remain high amongst those with HIV

Hospital admissions remain high amongst patients with HIV, even in the era of modern antiretroviral therapy, investigators from the US military report in the online edition of the Journal of Acquired Immune Deficiency Syndromes.

Treatment 08/03/2010

Viral load in early HIV infection predicted by that of transmitting partner

Viral load in individuals recently infected with HIV is closely related to that of the individual who transmitted the virus, US investigators report in the online edition of AIDS.

Treatment 05/03/2010

Daily treatment with valganciclovir reduces immune activation in HIV positive people with cytomegalovirus

Daily treatment with the anti-herpes drug valganciclovir for 8 weeks led to a significant reduction in CD8 T-cell immune activation in HIV positive people coinfected with cytomegalovirus. C-reactive protein levels appeared to decline, but other inflammation biomarkers remained stable.

Treatment 05/03/2010

MRSA rates six times higher in people with HIV

Rates of community-associated methicillin-resistant Staphylococcus aureus infection are significantly higher in the Chicago area among people with HIV than in people who are HIV negative.

Treatment 05/03/2010

Adding raltegravir does not clear persistent low-level HIV-1 viremia

"The persistence of viremia despite antiretroviral intensification suggests that residual viremia is not the product of ongoing cycles of HIV replication. In such a scenario, HIV eradication will require new approaches to complement combination antiretroviral therapy."

Treatment 04/03/2010

Abortion pill for HIV doesn’t pan out in study

While the scientific rationale behind using mifepristone as an HIV-fighting agent has piqued the interest of researchers for several years, the results of a clinical trial have been published, indicating that its therapeutic potential for this indication remains unclear.

Treatment 04/03/2010

Conjugate vaccine prevents recurrent pneumococcal disease in HIV

The 7-valent pneumococcal conjugate vaccine cuts the risk of recurrent invasive Streptococcus pneumoniae infection in HIV patients, according to a study from Malawi.

Treatment 03/03/2010

Stopping tenofovir doesn’t always reverse kidney damage

Kidney damage caused by tenofovir may not reverse itself after a year of discontinuing the drug.

Treatment 03/03/2010

HIV associated with poorer sexual function for women

Sexual function is poorer in HIV-positive women than in women who are HIV-negative, US investigators report in a study published in the online edition of the Journal of Acquired Immune Deficiency Syndromes.

Treatment 03/03/2010

Smoking is sole risk for lung cancer for women with HIV

Cigarette smoking was the sole risk factor for the development of lung cancer in women with or at risk of HIV in a study published in the online edition of the Journal of Clinical Oncology.

Treatment 02/03/2010

HIV therapies have varied impacts on cerebral functioning

Highly active antiretroviral therapy (HAART) regimens have differing effects on cerebral function in treatment-naive HIV patients, a multinational research team has found.

Treatment 02/03/2010

Symptoms associated with increased risk of viral load rebound in patients taking HIV treatment

A high burden of physical and psychological symptoms is associated with an increased risk of viral load rebounding to detectable levels in patients taking HIV treatment, UK investigators report in the online edition of the Journal of Acquired Immune Deficiency Syndromes.

Treatment 01/03/2010

Tenofovir tied to renal problems in children with HIV

Prolonged use of tenofovir by children with HIV infection is linked with hypophosphatemia in a small percentage of cases, according to researchers.

Treatment 01/03/2010

Tenofovir-associated kidney problems not always reversible

Kidney function does not always return to normal after treatment with tenofovir is discontinued because of renal toxicities, Australian investigators report in an advance online publication in the Journal of Acquired Immune Deficiency Syndromes.

Treatment 26/02/2010

Research sheds new light on HIV in the gut

Different forms of HIV genetic material are concentrated in different parts of the gastrointestinal tract, and HIV behavior and immune response appears different in the gut than in the blood.

Treatment 26/02/2010

Suppressive antiretroviral therapy slows progression of atherosclerosis

Antiretroviral therapy that reduces viral load to an undetectable level was linked to slower progression of sub-clinical atherosclerosis.

Treatment 26/02/2010

CD4 counts declining more rapidly among recent seroconverters in US military cohort

In a study of over 1000 mostly male seroconverters in the United States military, CD4 cell counts appear to be declining more quickly in those who seroconverted in more recent years.

Treatment 25/02/2010

Bone fracture risk higher among people living with HIV

People living with HIV face a higher risk of bone fractures than people of similar ages in the general population.

Treatment 24/02/2010

Elvitegravir use similar in adolescents and adults

Once-daily elvitegravir — when added to a protease inhibitor-based background regimen — may be as effective and tolerable in adolescents as it is in adults, according to findings presented at the 17th Conference on Retroviruses and Opportunistic Infections, held in San Francisco.

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